联合降阶梯疗法治疗婴幼儿喘息的临床效果

Clinical effect of combined step down therapy in the treatment of infant wheezing

目的研究联合降阶梯疗法治疗婴幼儿喘息的可行性和安全性。方法选择2017年3月-2019年6月广东省江门市新会区第二人民医院收治的婴幼儿喘息患者150例,随机分为观察组和对照组各75例。对照组接受常规治疗,观察组接受联合降阶梯疗法治疗。比较两组患儿治疗前、治疗3 d和7 d后喘息症状体征评分、治疗有效率、28 d内喘息复发率。结果观察组治疗后3 d、7 d患儿喘息症状体征评分均低于对照组,差异均有统计学意义(P<0.05)。观察组治疗总有效率为96.00%,高于对照组的86.67%,差异有统计学意义(P<0.05)。观察组28 d内喘息复发率10.67%,低于对照组的22.67%,差异有统计学意义(P<0.05)。结论联合降阶梯疗法治疗婴幼儿喘息效果较好,能有效缓解喘息症状,降低复发率,值得临床推广应用。

Objective To study the feasibility and safety of combined step down therapy in the treatment of infant wheezing. Methods One hundred and fifty infants with infant wheezing in the Sencond People’s Hospital of Xinhui District of Jiangmen City,Guangdong,from March 2017 to June 2019 were selected and randomly divided into observation group and control group with 75 cases in each group. The control group was given the conventional treatment,while the observation group was given combined step down therapy.The scores of wheezing symptoms and signs before treatment,3 days and 7 days after treatment,the effective rate of treatment and the recurrence rate of wheezing within 28 days were compared between the two groups. Results The scores of wheezing symptoms and signs in the observation group were lower than those in the control group after 3 days and 7 days of treatment,and the differences were statistically significant(P<0.05). The total effective rate of the observation group was 96.00%,which was higher than86.67% of the control group,and the difference was statistically significant(P<0.05). The recurrence rate of wheezing in the observation group within 28 days was 10.67%,which was lower than 22.67% of the control group,and the difference was statistically significant(P<0.05). Conclusion Combined step down therapy in the treatment of infantile wheezing had a good effect,which could effectively relieve the wheezing symptoms and reduce the recurrence rate, which was worthy of clinical promotion and application.