白塞病的临床诊治进展

Progress in clinical diagnosis and treatment of Beh?et’s disease

白塞病(Behcet’s disease,BD)是累及全身各系统和脏器的自身免疫性疾病,目前病因尚不明确。近年来,学者在遗传学、免疫学方面的研究不断取得新的发现,其在BD免疫调控机制中亦发挥着重要的作用。目前BD的治疗方案以激素和免疫抑制剂为主,部分新型生物制剂亦在难治型BD中逐渐占有一席之地。本文针对BD的发病机制、病因及治疗方案等的研究进展作一综述。

Behcet’s disease(BD) is an autoimmune disease involving all systems and organs of the body.The etiology is still unclear.In recent years,researchers have made new discoveries in genetics and immunology,which also play an important role in the immune regulation mechanism of BD.At present,hormone and immunosuppressive agents are the main treatment options for BD,and some new biological agents have gradually occupied a place in refractory BD.This article reviewed the pathogenesis,etiology and treatment of BD.