立体定向放疗在晚期NSCLC伴寡转移的应用

Stereotactic Body Radiotherapy for Oligometastatic Disease in Non-small Cell Lung Cancer

立体定向放疗(SBRT)因其具有非侵入性、高剂量率等优势而越来越多地用于非小细胞肺癌寡转移灶的治疗.临床上大量数据证实S B RT在非小细胞肺癌寡转移灶治疗的局部控制和无进展生存方面获益较大.该文探讨了寡转移的定义,回顾分析了SBRT治疗包括颅内、肺、肝和肾上腺等NSCLC特定部位转移灶的最新临床证据.

Stereotactic body radiotherapy(SBRT)is increasingly used in the treatment of oligometastatic NSCLC due to its non-invasive conduct and ability to deliver high doses.Clinical evidence supporting the use of SBRT in oligometastatic NSCLC is emerging and consistently demonstrates significant benefit in local control and progressiofree survival.This paper discusses the definition of oligometastases,and reviews current available data on SBRT treatment in oligometastatic NSCLC including evidence for site-specific SBRT in intracranial,lung,liver,and adrenal metastases.