子宫动脉栓塞术在治疗子宫瘢痕妊娠中的临床疗效及安全性分析

Analysis of Clinical Efficacy and Safety of Uterine Artery Embolization in the Treatment of Uterine Scar Pregnancy

目的分析在治疗子宫瘢痕妊娠中子宫动脉栓塞术的临床应用效果与安全性。方法方便抽取该院自2018年1月-2019年11月收治的116例子宫瘢痕妊娠患者作为研究对象,以不同治疗措施作为分组依据,将116例患者分为对照1组、对照2组、观察组。对照1组38例用超声监护下清宫术联合米非司酮治疗,对照2组38例用超声监护下清宫治疗,观察组40例用子宫动脉栓塞术联合清宫术治疗,对比3组临床观察指标、治疗总有效率。结果观察组术中出血量(194.5±12.1)mL少于对照1组(217.3±12.2)mL、对照2组(218.3±12.5)mL,差异有统计学意义(F=47.350,P<0.05);观察组β-HCG值转阴时间(49.5±2.0)d短于对照1组、对照2组,差异有统计学意义(F=278.70,P<0.05),且术后β-HCG值(309.1±118.9)mmol/L低于对照1组、对照2组,差异有统计学意义(F=39.580,P<0.05);观察组治疗总有效率100.00%高于对照1组、对照2组,差异有统计学意义(χ^2=5.975,P<0.05)。结论在治疗子宫瘢痕妊娠中,子宫动脉栓塞术的应用,既可缩短β-hCG值转阴时间、改善β-hCG值,又可减轻对卵巢功能的影响、提高再次妊娠几率,临床应用效果显著。

Objective To analyze the clinical application effect and safety of uterine artery embolization in the treatment of uterine scar pregnancy.Methods A total of 116 patients with uterine scar pregnancy who were admitted to the hospital from January 2018 to November 2019 were conveniently selected as the research objects.Based on different treatment measures,the 116 patients were divided into control group 1 and control group 2 and the observation group.Control group 1 of 38 cases were treated with ultrasound monitoring combined uterine evacuation combined with mifepristone,control group 2 of38 cases were treated with ultrasound monitoring uterine evacuation,observation group of 40 cases were treated with uterine artery embolization combined with uterine evacuation,and the clinical observations between the three groups were compared Indicators,total effective rate of treatment.Results The intraoperative blood loss(194.5±12.1)mL of the observation group was less than the control group 1(217.3±12.2)m L,the control group 2(218.3±12.5)mL,and the difference was statistically significant(F=47.35,P<0.05);the observation groupβ-HCG value negative conversion time(49.5±2.0)d was shorter than that of control group 1 and control group 2,and the difference was statistically significant(F=278.7,P<0.05),and postoperativeβ-HCG value(309.1±118.9)mmol/L was lower than control group 1 and control group 2,and the difference was statistically significant(F=39.580,P<0.05);the total effective rate of treatment in the observation group was 100.00%higher than that of control group 1 and control group 2,and the difference was statistically significant(χ^2=5.975,P<0.05).Conclusion In the treatment of uterine scar pregnancy,the application of uterine artery embolization can not only shorten the time ofβ-hCG value to become negative,improveβ-hCG value,but also reduce the impact on ovarian function,increase the chance of pregnancy again,and the clinical application effect is significant.