临床早期干预和期待治疗对早发型重度子痫前期母儿结局的影响

The Influence of Early Clinical Intervention and Expectant Treatment on Maternal and Fetal Outcome of Early-onset Severe Preeclampsia

目的分析临床早期干预和期待治疗对早发型重度子痫前期母儿结局的影响。方法该次研究对象为方便选取该院妇产科的80例早发型重度子痫前期患者,研究时间2018年6月-2019年4月,依据是否采取孕期保健和临床干预措施进行分组,行孕期保健和临床干预的40例患者为观察组,未行孕期保健和临床干预的40例患者为对照组,对比两组患者并发症和围生儿结局。结果观察组产妇子痫、肾功能损害、心功能不全、肝功能损害以及产后出血等各类并发症的发生率均比较低,差异有统计学意义(χ^2=3.914、4.501、4.114、4.501、4.114、4.114,P<0.05);观察组围生儿出现新生儿窒息、新生儿死亡等不良结局的发生率均低于对照组,差异有统计学意义(χ^2=3.914、5.000、3.914,P<0.05),观察组围生儿体重是(1736.5±327.5)g,NICU住院时间(32.6±5.3)d,差异有统计学意义(t=4.170、14.363,P<0.05)。结论临床早期干预和期待治疗可以改善早发型重度子痫前期母儿结局,降低孕妇并发症和新生儿不良结局,最大限度保障母婴安全,降低子痫的发生率。

Objective To analyze the influence of early clinical intervention and expectant treatment on the maternal and fetal outcome of early-onset severe preeclampsia.Methods The subjects of this study were 80 patients with early-onset severe preeclampsia in the Department of Obstetrics and Gynecology in the hospital.The study period was from June 2018 to April 2019.The subjects were conveniently selected divided into two groups according to whether pregnancy health care and clinical intervention measures are taken.40 patients with clinical intervention were the observation group,and 40 patients who did not undergo pregnancy care and clinical intervention were the control group.The complications and perinatal outcomes of the two groups were compared.Results The incidence of various complications such as eclampsia,renal dysfunction,cardiac insufficiency,liver dysfunction,and postpartum hemorrhage in the observation group were relatively low.The difference was statistically significant(χ^2=3.914,4.501,4.114,4.501,4.114,4.114,P<0.05);the incidence of adverse outcomes such as neonatal asphyxia and neonatal death in the observation group was lower than that of the control group.The difference was statistically significant(χ^2=3.914,5.000,3.914,P<0.05),the perinatal weight of the observation group was(1736.5±327.5)g,and the hospitalization time of NICU was(32.6±5.3)d.Compared with the control group,the difference was statistically significant(t=4.170,14.363,P<0.05).Conclusion Early clinical intervention and expectant treatment can improve the maternal and child outcomes of early-onset severe preeclampsia,reduce the complications of pregnant women and adverse neonatal outcomes,maximize the safety of mothers and children,and reduce the incidence of eclampsia.