经导管溶栓及支架植入术治疗肠系膜上动脉缺血性疾病的临床疗效

Clinical Efficacy of Transcatheter Thrombolysis and Stent Implantation in the Treatment of Superior Mesenteric Artery Ischemic Disease

目的探讨经导管溶栓及支架植入术对肠系膜上动脉缺血性疾病的应用价值。方法回顾性分析2016年3月-2019年1月在该院接受治疗的50例肠系膜上动脉缺血性疾病患者的临床资料,依据治疗方式不同,分为对照组(经导管溶栓治疗,25例)与观察组(支架植入术治疗,25例),对比两组临床疗效、血液流变学指标及病死率情况。结果观察组总有效率(92.00%)高于对照组(64.00%),差异有统计学意义(χ^2=5.711,P=0.017);观察组血管再通率(96.00%)高于对照组(64.00%),差异有统计学意义(χ^2=8.000,P=0.005);观察组血浆黏度、全血黏度、HCT、D-二聚体值小于对照组,差异有统计学意义(P<0.05);观察组病死率(4.00%)低于对照组(32.00%),差异有统计学意义(χ^2=4.878,P=0.010)。结论支架植入术治疗肠系膜上动脉缺血性疾病的疗效优于经导管溶栓治疗,可有效改善患者的临床症状,降低病死率,促进患者快速康复。

Objective To investigate the application value of transcatheter thrombolysis and stent implantation for superior mesenteric artery ischemic disease.Methods The clinical data of 50 patients with superior mesenteric artery ischemic disease who were treated in the hospital from March 2016 to January 2019 were retrospectively analyzed.According to different treatment methods,they were divided into control group(transcatheter thrombolysis,25 cases)and the observation group(stent implantation treatment,25 cases),compare the clinical efficacy,hemorheology indicators and mortality of the two groups.Results The total effective rate(92.00%)of the observation group was higher than that of the control group(64.00%),and the difference was statistically significant(χ^2=5.711,P=0.017);the recanalization rate of the observation group(96.00%)was higher than that of the control group(64.00%),the difference was statistically significant(χ^2=8.000,P=0.005);the plasma viscosity,whole blood viscosity,HCT,and D-dimer values of the observation group were lower than those of the control group,and the difference was statistically significant(P<0.05);The fatality rate of the observation group(4.00%)was lower than that of the control group(32.00%),and the difference was statistically significant(χ^2=4.878,P=0.010).Conclusion Stent implantation is more effective than transcatheter thrombolysis in the treatment of superior mesenteric artery ischemic disease.It can effectively improve the clinical symptoms of patients,reduce the mortality rate,and promote rapid recovery of patients.