基于电感耦合等离子体质谱法的海洛因检材的关联性判别研究

Correlative Discrimination into Sorting Heroin Based on Inductively Coupled Plasma Mass Spectrometry

目的使用电感耦合等离子体质谱(ICP-MS)测定海洛因检材中无机元素,根据无机元素的含量对海洛因进行分类,实现案件串并。方法超声辅助溶解用于溶解海洛因检材。使用ICP-MS检测28种无机元素及其同位素。比较65种数据预处理的统计组合,使用层次聚类分析法分析所有数据。结果测定28种无机元素及其同位素的标准曲线,统计海洛因检材中的各元素的浓度范围。归一化/欧几里得距离的数据预处理组合方式为最好的统计组合方式。对33个海洛因样本进行层次聚类分析(HCA),判断样本之间的联系。结论本文使用ICP-MS法测定海洛因中的无机元素,可同时测定多种元素,方法简便快速。使用优化的数据处理方式,准确判断检材之间的联系,为案件侦破提供情报。

Objective To analyze the elements in seized heroin samples with inductively coupled plasma-mass spectrometry(ICP-MS)to determine the contents of tested elements and therewith categorize the samples so as to have the relevant cases clustered.Methods Ultrasonic-assisted dissolution was used to prepare the heroin samples from which ICP-MS was optimized to simultaneously quantify 28 elements and their isotopes.Sixty-fi ve statistical combinations were compared and consecutively analyzed into all the obtained data with hierarchical cluster analysis(HCA).Results Standard curves were established for determination of 28 elements and their isotopes.For all the heroin samples analyzed through ICP-MS,their harbored elements were obtained of each one’s respective concentration range.Data pre-processing of normalization followed by Euclidean distance was found to be the best statistical compromise for optimal discrimination on whether the samples are correlated.Resultant from HCA to analyze the data of 33 heroin samples,the corresponding cases were classifi ed.Conclusions Multiple elements harbored in heroin can be determined with ICP-MS simultaneously and quickly,valuable of providing intelligence for cases connection and/or relevance with their disclosed correlation of the involving samples.