摘要
目的了解新疆乌鲁木齐某三甲医院体检儿童的脂溶性维生素营养状况,并提出营养补充及疾病预防的合理建议。方法选取171名参加健康体检的0~16岁儿童为研究对象,采用液相色谱串联质谱(LC-MS/MS)法检测血样中维生素A,E,D和K的含量。结果25-(OH)D的极度缺乏、缺乏和不足总人数构成比随年龄增长而增加,学龄期构成比最高(17.0%),3组间差异有统计学意义(χ~2=9.503,P<0.05);学龄前组维生素K缺乏者构成比最高(7.0%),婴幼儿组维生素K过量者构成比最高(4.7%),3组间差异有统计学意义(χ~2=18.789,P<0.05)。结论定期检查儿童脂溶性维生素含量十分必要,适量且及时地补充维生素对预防疾病有重要意义。
Objective To investigate the nutritional status of fat-soluble vitamins of children taking physical examination in a hospital in Urumqi of Xinjiang,and put forward reasonable suggestions for nutritional supplementation and disease prevention.Methods Totally 171 healthy children aged 0-16 years were selected as the study objects and the contents of vitamin A,E,D and K in their blood samples were detected by liquid chromatography tandem mass spectrometry(LC-MS/MS).Results The proportion of children with extreme scarcity,deficiency and short of 25-(OH)D increased with the age,and was the highest in children of school age(17.0%),with statistical difference(χ~2=9.503,P<0.05)among 3 groups.The proportion of children lacked vitamin K was the highest(7.0%)in preschool group,and over dosed vitamin K was the highest(4.7%)in infant group,with statistical difference(χ~2=18.789,P<0.05)among 3 groups.Conclusions It is necessary to examine fat-soluble vitamins of children regularly,and proper and timely supplementation of vitamins is of significance for disease control and prevention.
出处
《疾病预防控制通报》
2020年第5期32-35,共4页
Bulletin of Disease Control & Prevention(China)
基金
新疆维吾尔自治区自然科学基金面上项目(2017D01C225)。
