基于自我康复微信小程序的中医综合疗法联合西黄解毒胶囊治疗乳腺癌创伤后应激障碍60例临床观察

Clinical Observation on the Treatment of 60 Cases of Post-traumatic Stress Disorder of Breast Cancer by Comprehensive Therapy of Traditional Chinese Medicine Combined with Xihuang Jiedu Capsule(西黄解毒胶囊):Based on a Self-Healing We Chat Applet

目的观察基于自我康复微信小程序的中医综合疗法在乳腺癌创伤后应激障碍中的应用效果。方法将120例乳腺癌创伤后应激障碍患者随机分为试验组和对照组各60例。对照组给予西黄解毒胶囊每次0.5g口服,每日3次;试验组在对照组干预基础上配合基于自我康复微信小程序的中医综合疗法干预(包括中医心理疗法、五音疗法、放松训练、饮食调摄、磁珠耳穴贴压),每周3次自我康复训练。两组均干预12周。评估干预前后患者的创伤后应激障碍自评量表(PCL-C)、生活质量量表(FACT-B)、匹兹堡睡眠质量指数量表(PSQI)、汉密顿抑郁量表(HAMD)评分变化,以评价患者睡眠质量、不良情绪及生活质量改善情况。结果与干预前相比,干预后两组患者PCL-C、FACT-B、PSQI、HAMD评分均有改善(P<0.05);与对照组相比,干预后试验组患者PCL-C、PSQI、HAMD评分降低,FACT-B评分升高(P<0.05)。结论基于自我康复微信小程序的中医综合疗法联合西黄解毒胶囊有助于改善乳腺癌创伤后应激障碍患者抑郁等不良情绪,提高患者生活质量。

Objective To observe the application efficacy of comprehensive Chinese medicine(TCM) therapy in post-traumatic stress disorder(PTSD) of breast cancer based on self-healing WeChat applet. Method A total of 120 breast cancer patients with PTSD were randomized into a test group and a control group, with 60 patients in each group. The control group was treated with Xihuang Jiedu Capsule(西黄解毒胶囊) 0.5 g orally once, 3 times a day. On the basis of intervention control group, the test group added with comprehensive TCM interventions based on self-healing WeChat applet including TCM psychotherapy, five-tone therapy, relaxation training, diet adjustment, and magnetic ear acupunctur, and self-rehabilitation training 3 times a week. Both groups intervened for 12 weeks. The post-traumatic stress disorder self-rating scale(PCL-C), quality of life scale(FACT-B), Pittsburgh Sleep Quality Index(PSQI), and Hamilton Depression Scale(HAMD) scores, patient′s sleep quality, bad mood and quality of life improvement were evaluated before and after intervention. Results Compared with those before intervention, PCL-C, FACT-B, PSQI, and HAMD scores of both groups of improved after intervention(P<0.05);compared with the control group, PCL-C, PSQI, and HAMD scores of the test group after the intervention decreased, while the FACT-B score increased(P<0.05). Conclusion Comprehensive TCM therapy combined with Xihuang Jiedu Capsules based on self-healing WeChat applet can help improving depression and other negative emotions of patients with breast cancer PSTD, and improving the quality of life.