荧光素钠及吲哚菁绿血管造影在颅内动脉瘤夹闭术中的应用对比

A Comparative Study of Intraoperative Application of Fluorescein and Indocyanine Green Videoangiography in Intracranial Aneurysm Clipping Surgery

目的 探讨荧光素钠血管造影(fluorescein videoangiography,FL-VA)与吲哚菁绿血管造影(indocyanine green videoangiography,ICG-VA)在颅内动脉瘤术中不同的应用效果.方法 回顾性分析2019年1月-2020年1月间在我院接受颅内动脉瘤夹闭术的65例患者,在动脉瘤夹闭后先行FL-VA,再行ICG-VA,分别用两种造影结果判断动脉瘤是否夹闭完全、载瘤动脉是否狭窄以及瘤周穿支动脉是否通畅.结果 65例患者中,30例FL-VA及ICG-VA结果一致,10例FL-VA在显示细小穿支血管(2例颈内动脉后交通动脉动脉瘤及3例前交通动脉动脉瘤)及判断动脉瘤是否夹闭完全(3例大脑中动脉动脉瘤,1例颈内动脉后交通动脉动脉瘤及1例大脑前动脉远端动脉瘤)方面较ICG-VA有明显优势.因吲哚菁绿在血管内清除快,25例动脉瘤夹闭术中短时间内重复进行ICG-VA,但FL-VA无法重复进行.结论 FL-VA较ICG-VA能更清晰地显示穿支血管,准确判断动脉瘤是否夹闭完全,但缺点是无法短时间内重复行FL-VA.

Objective To compare the application of fluorescein videoangiography(FL-VA)and indocyanine green videoangiography(ICG-VA)in intracranial aneurysm surgery.Methods A total of 65 patients who underwent aneurysm clipping in our hospital from January 2019 to January 2020 were included in the study.FL-VA and ICG-VA were used during the surgery to determine whether the aneurysm is completely clipped and the artery bearing the aneurysm and the perforating artery around the aneurysm are unobstructed.Results All 65 patients underwent both FLVA and ICG-VA intraoperatively after aneurysm clipping.FL-VA was applied first.In 30 cases,FL-VA and ICG-VA provided the same results.In 10 cases,FL-VA performed obviously better over ICG-VA in visualizing small perforating arteries(2 cases of internal carotid artery-posterior communicating artery aneurysms and 3 cases of anterior communicating artery aneurysm)and evaluating whether the aneurysm was completely clipped(3 cases of middle cerebral artery aneurysm,1 case of internal carotid artery-posterior communicating artery aneurysms and 1 case of distal anterior cerebral artery aneurysm).In the remaining 25 cases,ICG-VA was repeatedly applied in a short period of time due to quick clearance of indocyanine green from the blood vessels,but this couldn't be done with FL-VA.Conclusions Compared with ICG-VA,FL-VA can provide better visualization of perforating artery,and can determine whether the aneurysm was completely clipped more accurately.However FL-VA couldn't be repeatedly applied during a short period of time.