摘要
铁死亡是以铁依赖性的、细胞内氧化堆积为主要特征的新型细胞死亡方式。目前研究表明铁死亡参与神经毒性损伤、肿瘤、心血管疾病等多种疾病的发生发展过程。我们围绕铁死亡的发生机制及其与相关疾病的关系进行综述。
Ferroptosis is a new programmed cell death characterized by iron dependent and intracellular oxidative accumulation.Current studies have confirmed that ferroptosis is involved in the occurrence and development of neurotoxicity injury,tumors,cardiovascular diseases and other diseases.This paper reviews the mechanisms of ferroptosis and its role in related diseases based on recent studies.
作者
牟英文
栗子渊
杨旭
陈尚雅
侯姗姗
张恩国
邵华
杜忠君
Mou Yingwen;Li Ziyuan;Yang Xu;Chen Shangya;Hou Shanshan;Zhang Enguo;Shao Hua;Du Zhongjun(Shandong Academy of Occupational Health and Occupational Medicine,Shandong First Medical University&Shandong Academy of Medical Sciences,Jinan 250062,China;School of Public Health,Changchun University,Changchun 130021,China)
出处
《中华劳动卫生职业病杂志》
CAS
CSCD
北大核心
2020年第10期797-800,共4页
Chinese Journal of Industrial Hygiene and Occupational Diseases
基金
国家自然科学基金(81602893)
山东省自然科学基金(ZR2015YL049)
山东省医药卫生科技发展计划(2016WS0581470145)
山东省医学科学院创新工程。
