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IUI精液优化处理助孕效果及对妊娠结局的影响分析 被引量:1

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摘要 目的探讨宫腔内人工授精(IUI)精液优化处理助孕效果及对妊娠结局的影响。方法选取2016年9月-2020年4月来我院进行IUI助孕的夫妻140对,对患者的精液采用Diff-Quik染色法检测精子畸形率,并分析精子形态优化处理前后与IUI临床妊娠率的关系。结果在280个IUI治疗周期中精子畸形率高于正常值的有125个周期,精液优化处理前平均正常形态精子率低于精液优化处理后的正常形态精子率(P<0.05),精液优化处理前的平均精子畸形指数、畸形精子指数与处理后的均无显著差异(P>0.05)。精液优化处理后正常形态精子率仍未达标的82个治疗周期中,IUI临床妊娠16例,临床妊娠率为19.51%,处理后精子正常形态率达标的75个治疗周期中,采用人工授精后临床妊娠9例(12.00%),无显著差异(P>0.05)。结论在临床中,通过密度梯度离心法处理精液能够降低精子畸形率,但采用密度梯度离心法处理后的精子畸形率高低与IUI妊娠结局没有直接的关系。
出处 《基层医学论坛》 2020年第34期4952-4953,共2页 The Medical Forum
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  • 1黄玉玲,龙晓林,杜红姿.Pure Sperm梯度离心法和上游法处理精液效果的比较[J].广东医学,2005,26(4):492-494. 被引量:5
  • 2ESHRE Capri Workshop Group. Intrauterine insemination [J]. Hum Reprod Update,2009,15(3) 265 277.
  • 3Tomlinson MJ, Amissah Arthur JB, Thompson KA, et al. Prog nostic indicators for intrauterine insemination (IUI) = statistical model for IUI success[J]. Hum Reprod,1996,11 (9) :1892-1896.
  • 4Farimani M,Amiri I. Analysis of prognostic factors for successful outcome in patients undergoing intrauterine insemination[J]. Acta Med Iran,2012,45(2) 101 106.
  • 5Guven S, Gunalp GS, Tekin Y. Factors influencing pregnancy rates in intrauterine insemination cycles[J]. J Reprod Med, 2008, 53(4):257 265.
  • 6Merviel P, Heraud MH, Grenier N, et al. Predictive factors for pregnancy after intrauterine insemination (IUI) : an analysis of 1038 cycles and a review of the literature[J]. Fertil Steril, 2010, 93(1) : 79-88.
  • 7Van Voorhis BJ, Barnett M, Sparks AE, et al. Effeet of the total motile sperm count on the efficacy and cost effectiveness of intra- uterine insemination and in vitro fertilization[J]. Fertil Steril, 2001,75(4):661 668.
  • 8World Health Organization. WHO laboratory manual for the ex amination and processing of human semen[M]. Cambridge Cam bridge University Press,2010. Demir B, Dilbaz B, Cinar O, et al. Factors affecting pregnancy out- come of intrauterine insemination cycles in couples with favoura- ble female characteristics[J]. J Obstet Gynaecol, 2011,31 (5) : 420- 423.
  • 9Andersen AN, Goossens V, Bhattacharya S, et al. Assisted repro ductive technology and intrauterine inseminations in Europe, 2005 results generated from European registers by ESHRE[J]. Hum Reprod,2009,24(6) 1267-1287.
  • 10Kolibianakis EM, Zikopoulos KA, Fatemi HM, et al. Endometrial thickness cannot predict ongoing pregnancy achievement in cycles stimulated with clomiphene citrate for intrauterine insemination [J]. Reprod Biomed Online,2004,8(1) =115-118.

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