原发性干燥综合征肾脏损害的研究进展

Research Progress in Renal Injury Relevant to Primary Sjögren’s Syndrome

肾脏是原发性干燥综合征重要的腺体外受累器官,由于多数患者早期症状隐匿,易造成漏诊。本文从原发性干燥综合征肾脏损害的流行病学、临床特征、病理特征、治疗及预后综述了近年来原发性干燥综合征肾脏损害的研究进展。定期的肾功能筛查,必要时行肾活检以提高诊断效率,并根据不同病理类型、临床特征制定有效的治疗方案,同时还需警惕预后的不利因素。

The kidney is an important extra-glandular affected organ in primary Sjögren’s syndrome.Due to the concealment of early symptoms in most patients,it is easy to cause missed diagnosis.This paper reviews the research progress of renal damage in primary Sjögren’s syndrome in recent years from the epidemiology,clinical features,pathological features,treatment,and prognosis.Patients should get a regular screening of renal function,and if necessary taking renal biopsy,to improve the efficiency of diagnosis.Effective treatment should be made according to different pathological types and clinical features,at the same time,adverse factors of prognosis should be aware of.