炎症因素与脑梗死患者颈动脉粥样硬化的相关性研究

Research on the Clinical Correlation of Inflammatory Factors with Carotid Atherosclerosis in Cerebral Infarction Patients

目的:研究炎症因素与脑梗死患者颈动脉粥样硬化的相关性。方法:选择笔者所在医院2018年9月-2019年9月治疗的80例脑梗死患者,其中出现颈动脉粥样硬化44例患者为研究组,未出现颈动脉粥样硬化36例患者为对照组,观察两组炎症因素与颈动脉粥样硬化的关系。结果:两组红细胞沉降率、单核细胞比例、纤维蛋白原比较差异均有统计学意义(P<0.05);将上述资料带入Logistic回归方程进行计算显示,单核细胞比例高、红细胞沉降率高及纤维蛋白原高均是引起脑梗死患者发生颈动脉粥样硬化的独立危险因素(P<0.05)。结论:脑梗死患者发生颈动脉粥样硬化概率较高,目前炎症因素与出现颈动脉粥样硬化之间存在一定联系,可通过炎症因素进行起到治疗与预防的作用,降低颈动脉粥样硬化发生率。

Objective:To study the correlation of inflammatory factors with carotid atherosclerosis(AS)in cerebral infarction patients.Method:A total of 80 patients with cerebral infarction treated in our hospital from September 2018 to September 2019 were selected,including 44 patients with carotid atherosclerosis were as the study group,and 36 patients without carotid atherosclerosis were as the control group.The relationship between inflammatory factors and carotid atherosclerosis in the two groups was observed.Result:There were statistically significant differences in erythrocyte sedimentation rate,monocyte ratio and fibrinogen between the two groups(P<0.05).The above data were put into the Logistic regression equation for calculation,and the results showed that high monocyte ratio,high erythrocyte sedimentation rate and high fibrinogen were independent risk factors for carotid atherosclerosis in patients with cerebral infarction(P<0.05).Conclusion:The incidence of carotid atherosclerosis in patients with cerebral infarction is relatively high.At present,there is a certain relationship between inflammatory factors and the occurrence of carotid atherosclerosis,which can play a role of treatment and prevention through inflammatory factors and reduce the incidence of carotid atherosclerosis.