补肾乐眠汤联合性激素替代疗法对围绝经期失眠患者激素水平及睡眠质量的影响

Effects of Bushenlemian Decoction Combined with Hormone Replacement Therapy on Hormone Levels and Sleep Quality in Peri-menopausal Insomnia Patients

目的:探讨补肾乐眠汤联合性激素替代疗法对围绝经期失眠患者效果观察。方法:选取2018年7月至2019年7月福建省福州市长乐区妇幼保健院收治的围绝经期失眠患者116例作为研究对象,采用盲抽法分为对照组和观察组,每组58例。对照组采用性激素替代疗法治疗,在对照组基础上,观察组给予补肾乐眠汤治疗。比较2组激素水平与睡眠质量。结果:治疗4周后,观察组FSH、LH水平均较对照组低,观察组PSQI评分较对照组低,差异有统计学意义(P<0.05)。结论:补肾乐眠汤联合性激素替代疗法可调节围绝经期失眠患者激素水平,改善睡眠质量。

Objective:To explore the effect of Bushen lemian decoction combined with sex hormone replacement therapy on perimenopausal insomnia.Methods:From July 2018 to July 2019,116 patients with perimenopausal insomnia were randomly divided into Observation Group(n 58)and Control Group(N 58).The control group was treated with hormone replacement therapy,and the observation group was treated with Bushen Lemian decoction.Hormone levels and sleep quality were compared between the two groups.Results:After 4 weeks of treatment,the levels of FSH and LH in the observation group were lower than those in the control group,and the PSQI score in the observation group was lower than that in the control group,with a statistically significant difference(P<0.05).Conclusion:Bushen lemian decoction combined with sex hormone replacement therapy can regulate hormone level and improve sleep quality of perimenopausal insomnia patients.