糖基化与宫颈癌及其临床应用的研究进展

Advances in research on glycosylation and cervical cancer and its clinical application

宫颈癌是临床上常见的恶性肿瘤之一,宫颈癌细胞的侵袭与转移是患者死亡的重要原因。糖基化异常与宫颈癌的发生、侵袭转移、免疫逃逸等密切相关。该文就糖基化与宫颈癌发生发展的可能机制及其在宫颈癌临床诊治的相关应用进行了阐述。

Cervical cancer is one of the most common malignant tumors in clinics.Invasion and metastasis of cervical cancer cells is an important cause of death.The abnormal glycosylation is closely related to the occurrence,invasion,metastasis and immune escape of cervical cancer.In this paper,the possible mechanisms of glycosylation and the occurrence and development of cervical cancer and its related application in the clinical diagnosis and treatment of cervical cancer are reviewed.