苇茎汤加减治疗痰热壅肺型肺炎的疗效观察

Observation on the curative effect of combination of traditional chinese and western of weijing decoction in treating pneumonia of phlegm heat obstructing lung type

目的:探讨苇茎汤加减对痰热壅肺型肺炎的临床疗效。方法:收集2017年6月—2019年12月痰热壅肺型肺炎患者82例,随机分为对照组和观察组,每组41例。对照组给予常规西药治疗,观察组在对照组基础上给予苇茎汤辨证加减治疗。两组患者均连续治疗两周,评价两组患者治疗前后肺部感染评分(CPIS)、中医症候积分、症状恢复时间、外周血炎症指标[白细胞(WBC)、C反应蛋白(CRP)、降钙素原(PCT)]及治疗有效率。结果:观察组患者总有效率为82.93%,对照组为56.10%,差异具有统计学意义(P<0.05);治疗后两组患者CPIS和中医症候积分均较治疗前下降(P<0.05),且观察组明显低于对照组,差异有统计学意义(P<0.05);观察组咳嗽、咳痰、喘息、肺部啰音消失时间、体温恢复正常时间及影像学示肺部炎症吸收时间均少于对照组,差异有统计学意义(P<0.05);治疗后两组患者外周血炎症指标WBC,CRP,PCT较治疗前均显著降低(P<0.05),且观察组明显低于对照组,差异有统计学意义(P<0.05)。治疗期间观察组无不良反应出现,对照组有3例患者出现腹泻,停药后症状缓解。结论:苇茎汤加减联合西药治疗痰热壅肺型肺炎,可有效提高治疗效果,提高患者生活质量,且无不良反应。

Objective:To observe the clinical efficacy of western of weijing decoction in treating pneumonia of phlegm heat obstructing lung type.Methods:All 82 cases of pneumonia of phlegm heat obstructing lung type patients from June 2017 to December 2019 in hospital were selected as the research objects.According to the time of admission,they were divided into control group and observation group with 41 cases in each group.The control group was treated with conventional western medicine and the treatment group was treated with weijing Decoction based on syndrome differentiation.Two groups of patients were treated for two weeks,and the pulmonary infection score,TCM symptom score,symptom recovery time,peripheral blood inflammation index(WBC,CRP,PCT)and treatment efficiency were evaluated before and after treatment.Results:Two weeks later,the total effective rate of the treatment group was 82.93%,and that of the control group was 56.10%,the difference was statistically significant(P<0.05).After treatment,the CPIS score of the two groups was lower than that before treatment(P<0.05),but the difference was statistically significant(P<0.05).After treatment,the scores of TCM symptoms in the two groups were lower than that before treatment(P<0.05),but the scores in the treatment group were significantly lower than that in the control group(P<0.05).After treatment,the time of cough,expectoration,wheezing,disappearance of lung rales,recovery of body temperature and absorption of pulmonary inflammation in the treatment group were shorter than those in the control group(P<0.05).After treatment,WBC,CRP and PCT were significantly lower in the two groups than before treatment(P<0.05),but the difference between the two groups was statistically significant(P<0.05).During the treatment,there were no adverse reactions in the treatment group and diarrhea in three patients in the control group.Conclusion:weijing decoction combined with western medicine treatment can effectively improve the treatment effect of phlegm heat damming lung type pneumonia,improve the quality of life of patients,and no adverse reactions.