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DC方案与CEF方案分别联合曲妥珠单抗靶向治疗晚期乳腺癌患者的效果比较

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摘要 目的:比较DC方案(多西他赛+卡铂)与CEF方案(环磷酰胺+表柔比星+氟尿嘧啶)分别联合曲妥珠单抗靶向治疗晚期乳腺癌患者的效果。方法:选取60例乳腺癌女性患者作为研究对象,采用随机数字表法将其分为观察组和对照组各30例。对照组给予曲妥珠单抗靶向治疗联合DC方案化疗,观察组给予曲妥珠单抗靶向治疗联合CEF方案化疗,比较两组临床疗效、生命质量评分及治疗期间不良反应发生率。结果:两组疾病缓解率及疾病控制率比较,差异均无统计学意义(P>0.05);治疗后,观察组生理功能、生理职能、躯体疼痛、一般健康状况、精力、社会功能、情感职能、精神健康等8个维度的生命质量评分均高于对照组,差异有统计学意义(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:DC化疗方案和CEF化疗方案联合曲妥珠单抗靶向治疗晚期乳腺癌患者的效果相当,但CEF化疗方案联合曲妥珠单抗靶向治疗提高晚期乳腺癌患者生命质量评分的效果优于DC化疗方案联合曲妥珠单抗靶向治疗。
作者 胡鸿波
出处 《中国民康医学》 2020年第20期110-112,共3页 Medical Journal of Chinese People’s Health
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