五音疗法干预失眠症患者睡眠质量效果的Meta分析

Meta-analysis of the Effect of Wuyin Therapy on Patients with Insomnia

目的调查中医五音疗法相比较单纯西医或中医常规疗法在治疗失眠症或其他疾病伴有睡眠障碍问题人群时的安全性和有效性。方法通过计算机检索和手工检索中国知网、万方、维普、sinomed等数据库,全面搜集国内外关于五音疗法对患者睡眠障碍影响的随机对照试验(Randomized Controlled Trial,RCT)。根据Cochrane系统评价方法,选择试验评价质量,而后采用RevMan 5.3软件和Stata16.0对有效数据进行Meta分析。结果最终纳入17项研究,共1246名受试对象。质量评价结果表明,17个研究的总体质量水平尚可。总体分析显示,在临床疗效(OR=2.421,95%CI:1.849~3.170,P<0.05)方面加有中医五音疗法治疗方案的临床疗效优于单纯西医或中医常规疗法。在匹兹堡睡眠质量指数(Pittsburgh Sleep Quality Index,PSQI)量表方面,增加有中医五音疗法的治疗组总评分优于单纯西医或中医常规疗法。结论中医五音疗法是改善患者睡眠障碍或睡眠质量的有效措施,在临床治疗中增加中医五音疗法,可有效治疗失眠症或者其他疾病伴随有睡眠障碍或睡眠质量差的问题。

Objective:This paper was to investigate Chinese medicine pentameter therapy in the treatment of patients with insomnia or other sleep disorders associated with disease crowd safety and efficacy compare to Western medicine or TCM than conventional therapy.Methods:Searching in computer and manual way based on China National Knowledge Infrastructure,Wangfang,Weipu sinomed and other databases,a comprehensive collection of randomized controlled trials on the effects of domestic and foreign pentameter therapy for sleep disorders(Randomized Controlled Trial,RCT).The Meta-analysis of valid data in accordance with the evaluation method of Cochrane,used by select quality evaluation tests and RevMan 5.3 software and Stata16.0.Results:17 studies included in the final total of 1246 subjects.Quality evaluation showed that the overall quality level of 17 research fair.Overall analysis showed clinical efficacy(OR=2.421,95%CI:1.849,3.170,P<0.05)added with respect clinical efficacy pentameter therapy programs better than western medicine or TCM conventional therapies.In(PSQI)scale aspects of the pittsburgh sleep quality index,have increased Chinese medicine pentameter therapy treatment group,the total score better than western medicine or Chinese medicine conventional therapy.Conclusion:Chinese medicine pentameter therapy is an effective measure to improve the quality of sleep in patients with sleep disorders or in the treatment of insomnia or other sleep disorders or diseases associated with poor sleep quality problem.