啶虫脒在榛子中的残留分析及膳食风险评估

Residue and Dietary Intake Risk Assessment of Acetamiprid in Hazelnut

[目的]为评价啶虫脒在东北地区特色小宗作物榛子中的使用安全性,开展啶虫脒在榛子中的残留量及残留降解研究。[方法]进行1年2地田间试验。消解动态试验按啶虫脒50 mg/kg(推荐最高剂量的1.5倍)施药;最终残留试验按50(推荐最高剂量的1.5倍)、33.3 mg/kg(推荐最高剂量)施药,施药2~3次,施药间隔15 d,2、3次施药均按照末次药后间隔28、35 d采集榛子样品。液相色谱串联质谱法对啶虫脒进行定量分析。[结果]田间消解动态试验表明:啶虫脒在榛子中消解较快,辽宁铁岭、抚顺2地的半衰期分别为2.2、3.3 d。膳食风险评估结果表明:啶虫脒在榛子中的残留风险处于安全水平。[结论]建议使用5%啶虫脒乳油防治榛瘿蚊,有效成分用药量25~33.3 mg/kg,于榛瘿蚊发生初期开始施药,最多施药2次,施药间隔10~15 d,安全间隔期28 d。

[Aims]This study aims to evaluate the safety of acetamiprid used in hazelnut,a characteristic small crop in Northeast China,the residues and decline dynamics of acetamiprid in hazelnut was determined.[Methods]The field trials in 2 fields for 1 year were carried out.For dissipation trial,acetamiprid was sprayed at the concentration of 50 mg/kg(1.5 times as the recommended highest concentrations).For final residue trial,acetamiprid was applied 2-3 times at the concentration of 50 mg/kg(1.5 times as the recommended highest concentrations)and 33.3 mg/kg(the recommended highest concentrations),respectively,with the spraying interval of 15 d.Hazelnut were collected after 28,35 d of the second,third treatment,respectively.Acetamiprid samples were analyzed with LC MS/MS.[Results]The result of the decline dynamics study showed that the half-life values(T1/2)were 2.2 and 3.3 d in Tieling and Fushun open field,respectively.The dietary risk assessment showed that acetamiprid was safe according to the low residual risk.[Conclusions]It is recommended that acetamiprid 5%EC be used to control Dasinura corylifalva in hazelnut at 25-33.3 mg/kg at early stage of D.corylifalva occurrence,with 28 days pre-harvest interval and 10-15 d application interval up to 2 times.