分子印迹光子晶体技术在食品检测中的应用研究进展

Research progress in the application of molecularly imprinted photonic crystal technology in food detection

在简述分子印迹技术、光子晶体技术和分子印迹光子晶体技术的基础上,对分子印迹光子晶体技术在食品有毒有害物质(兽药残留、农药残留、生物毒素、内分泌干扰物、非法添加物)和营养物质检测中的相关应用研究进行综述.指出:分子印迹光子晶体技术结合了分子印迹技术对目标物的高选择性和光子晶体独特的光学性质,作为新型光学传感器适用于食品检测领域;与传统的食品检测方法相比,分子印迹光子晶体技术在保证检测准确性的前提下极大地提高了可视化检测程度和检测效率,缩短了检测时间,更有利于现场检测的发展;然而,分子印迹光子晶体技术也存在合成过程较复杂、需要使用大量有机试剂、检测范围较窄、重复性较差等缺点.未来可就开发环境友好的绿色制备方法、增强光子晶体的稳定性和可控性、降低分子印迹光子晶体的非特异性吸附、开发适用于同时检测多种目标物的高通量检测方法、拓展在微生物检测领域的应用等方面作进一步研究,以优化和发展分子印迹光子晶体技术.

Based on the demonstration of molecular imprinting technology,photonic crystal technology and the technology of molecularly imprinted photonic crystal,the relevant researches on the application of molecularly imprinted photonic crystal technology in the detection of toxic and harmful substances in food(veterinary drug residues,pesticide residues,biological toxins,endocrine disruptors,illegal additives)and nutrients was combed.It pointed out that molecularly imprinted photonic crystal technology combined the high selectivity of molecular imprinting technology to the target and the unique optical properties of photonic crystals,and was suitable for food detection as a new optical sensor.Compared with the traditional food detection methods,molecularly imprinted photonic crystal technology greatly improved the detection efficiency,shortened the detection time,improved the visual detection degree,and was more conducive to the development of field detection.However,molecularly imprinted photonic crystal technology also had the disadvantages of complex synthesis process,large amount of organic reagents,narrow detection range and poor repeatability.Researchers could make further research in the future on developing environment-friendly green synthesis methods,enhancing the stability and controllability of photonic crystals,reducing the nonspecific adsorption of molecularly imprinted photonic crystals,developing high-throughput detection methods suitable for simultaneous detection of multiple targets,and expanding the application in the field of microbial detection to optimize and develop molecularly imprinted photonic crystal technology.