LED冷光源蓝光不同照射方式治疗新生儿高胆红素血症的临床比较

Clinical Comparison of Different Irradiation Methods of Blue Light with LED Cold Light Source in the Treatment of Neonatal Hyperbilirubinemia

目的探讨高胆红素血症新生儿采取LED冷光源蓝光间断照射治疗的临床效果及应用价值。方法该次研究时间范围为2019年1月—2020年3月,抽选该院收治高胆红素血症新生儿200例作为研究目标,根据入院时间先后编号后以单双数法分组,对照组新生儿(100例)采取冷光源蓝光持续照射方式治疗,观察组新生儿(100例)采取冷光源蓝光间断照射方式治疗,分别观察评估两组患儿治疗效果,记录各组患儿照射不同时间血清胆红素浓度变化及退黄时间,记录总光疗时间,对比统计学差异性;另外,该院新生儿室为有陪护病室,治疗的完成需要家长的配合,记录两组光疗家长的满意度。结果观察组患儿临床疗效与对照组差异无统计学意义(P>0.05)。两组患儿未接受治疗前血清胆红素浓度差异无统计学意义(P>0.05),光疗12 h与持续光疗24 h后胆红素均明显下降,观察组患儿退黄时间(3.02±1.07)d与对照组差异无统计学意义(P>0.05)。观察组总光疗时间(40.24±9.45)h明显低于对照组,差异有统计学意义(t=24.080,P<0.05)。另外,观察组患儿家长满意度93.00%明显高于对照组81.00%,差异有统计学意义(χ2=6.367,P<0.05)。结论高胆红素血症新生儿采取冷光源蓝光间断性照射方式治疗效果显著,总光疗时间较持续光疗明显缩短,且家长更满意。

Objective To investigate the clinical effect and application value of LED cold light source and blue light intermittent irradiation for newborns with hyperbilirubinemia.Methods The study time range is from January 2019 to March 2020.200 cases of neonates with hyperbilirubinemia in the hospital were selected as the research target.The newborns in the control group(100 cases)were treated with cold light source blue light continuous irradiation,and the observation group(100 cases)were treated with cold light blue light intermittent irradiation.Observe and evaluate the treatment effect of the two groups of children respectively,record the changes of serum bilirubin concentration and the time of yellowing at different times of irradiation in each group,record the total phototherapy time,and compare the statistical differences;in addition,the neonatal room in our hospital is an accompanying ward.The completion of the treatment requires the cooperation of parents,and the satisfaction of the two groups of phototherapy parents is recorded.Results There was not statistically significant difference in clinical efficacy between the observation group and the control group(P>0.05).There was not statistically significant difference in serum bilirubin concentration between the two groups before treatment(P>0.05),and the bilirubin decreased significantly after 12 h of phototherapy and 24 h of continuous phototherapy.There was not statistically significant difference between the observation group and the control group in yellowing time(3.02±1.07)d(P>0.05).The total phototherapy time of the observation group(40.24±9.45)h was significantly lower than that of the control group,the difference was statistically significant(t=24.080,P<0.05).In addition,93.00%of the parents in the observation group were satisfied,which was significantly higher than 81.00%in the control group,the difference was statistically significant(χ2=6.367,P<0.05).Conclusion Neonatal hyperbilirubinemia can be treated with cold light source and blue light intermittent irradiation.The total time of phototherapy is significantly shorter than that of continuous phototherapy,and the parents are more satisfied.