复合麻醉药对腹腔镜卵巢囊肿切除术后意识状态和认知功能影响分析

Effect of compound anesthetics on consciousness and cognitive function of patients after laparoscopic ovarian cyst resection

目的分析复合麻醉药对腹腔镜卵巢囊肿切除术后意识状态和认知功能的影响。方法 88例行腹腔镜卵巢囊肿切除术患者,根据麻醉药物不同分为常规组与实验组,每组44例。常规组患者联合维库溴铵、舒芬太尼、丙泊酚药物进行麻醉,实验组患者联合罗库溴铵、瑞芬太尼、咪唑安定进行麻醉,对比两组卵巢囊肿患者术后意识状态、认知功能评分以及麻醉不良反应发生率。结果实验组在拔管时、离开手术室时以及拔管1 h后意识状态评分分别为(3.4±0.5)、(4.1±0.5)、(4.7±0.4)分,均优于常规组的(2.1±0.4)、(3.4±0.8)、(4.1±0.4)分,差异有统计学意义(P<0.05)。术后1 h以及术后3 h,实验组患者认知功能评分高于常规组,差异有统计学意义(P<0.05)。两组患者不良反应发生率对比,差异无统计学意义(P>0.05)。结论罗库溴铵、瑞芬太尼、咪唑安定联合实施麻醉,有良好的麻醉效果,不仅药物起效速度快,而且也不会对患者的认知功能以及呼吸系统造成影响,具有临床应用价值。

Objective To analyze the effect of compound anesthetics on consciousness and cognitive function of patients after laparoscopic ovarian cyst resection.Methods A total of 88 patients after laparoscopic ovarian cyst resection were divided into conventional group and experimental group according to different anesthetics,with 44 cases in each group.Patients in the routine group were anesthetized with vecuronium bromide,sufentanil,and propofol,and patients in the experimental group were anesthetized with rocuronium bromide,remifentanil,and midazolam.The postoperative consciousness,cognitive function score and incidence of adverse anesthetic reactions were compared between the two groups.Results The scores of consciousness in the experimental group were(3.4±0.5),(4.1±0.5),(4.7±0.4)at the time of extubation,when leaving the operating room,and 1 h after extubation,which were better than those of the conventional group(2.1±0.4),(3.4±0.8),(4.1±0.4)points,and the difference was statistically significant(P<0.05).1 and 3 h after operation,the cognitive function score of the experimental group was higher than that of the conventional group,and the difference was statistically significant(P<0.05).There was no statistically significant difference in incidence of adverse reactions between the two groups(P>0.05).Conclusion The combined anesthesia of rocuronium bromide,remifentanil,and midazolam has a good anesthetic effect,which not only takes effect quickly,but also does not affect the patient’s cognitive function and respiratory system,which has clinical application value.