3.0T磁共振多种功能成像技术在前列腺癌诊断中的应用价值研究

The Application of 3.0T MRI in the Diagnosis of Prostate Cancer

目的研究3.0T磁共振成像常规扫描、弥散加权成像扫描(DWI)和波谱成像扫描(MRS)对前列腺癌的诊断价值。方法纳入汕头潮南民生医院接受治疗的前列腺癌患者52例,对所有患者均进行磁共振常规扫描、DWI和MRS,比较病灶感兴趣区域DWI信号强度、表观弥散系数(ADC)值以及(Cho+Cre)/Cit值。结果与正常周围带或者移行带相比,前列腺癌经DWI检测的ADC值显著降低,为[0.69±0.05)×10-3mm2/s(95%CI=(0.73-0.82)×10-3mm2/s,P<0.05];前列腺癌经MRS检测的(Cho+Cre)/Cit值显著升高,为1.69±0.42(95%CI=0.72~1.85,P<0.05)。结论3.0T磁共振成像弥散加权扫描获取的ADC值和波谱成像获取的(Cho+Cre)/Cit值可用于诊断前列腺癌,且效果较好。

Objective To study the diagnostic value of conventional scanning,diffusion weighted imaging(DWI)and spectral imaging(MRS)in prostate cancer.Methods A total of 52 patients with prostate cancer treated in Shantou Chaonan Minsheng hospital were enrolled in this study.All patients underwent conventional MRI scan,DWI and Mrs.DWI signal intensity,apparent diffusion coefficient(ADC)value and(CHO+CRE)/CIT value were compared.Results compared with the normal peripheral zone or transitional zone,the ADC value of DWI in prostate cancer was significantly lower(0.69±0.05)×10-3 mm2/S[95%CI=(0.73-0.82)×10-3 mm2/s,P<0.05];the(CHO+CRE)/CIT value of prostate cancer detected by MRS was significantly increased,which was 1.69±0.42(95%CI=0.72-1.85,P<0.05).Conclusion ADC and(CHO+CRE)/CIT values obtained by 3.0 T MR diffusion weighted imaging and(CHO+CRE)/CIT values obtained by spectral imaging can be used for the diagnosis of prostate cancer,and the effect is good.