新型冠状病毒肺炎早期临床及肺部影像学征像分析

目的探讨断型冠状病毒肺炎(COVID-19)患者的早期临床及及影像学特征。方法回顾性分析2020年I月22日至2020年2月10日35例经临床确诊的COVID-19患者的流行病学史、首次临床症状、白细胞和淋巴细胞计数、影像学表现及演变情况。结果35例患者中29例(83%)患者具有流行病学史,白细胞计数减低10例,升高1例;淋巴细胞计数减低16例,升高1例。34例患者出现临床症状,其中表现为发热34例,乏力、肌痛9例,干咳18例,咽痛3例。35例首次CT表现:正常2例,表现为肺炎33例。病变累及单侧肺4例,累及两肺29例;表现为斑片状磨玻璃影30例,主要位于胸膜下;胸膜下条索影2例;两肺下叶为实变影伴周围磨玻璃影及支气管充气征1例。3~6d胸部CT复查:病变进展18例(包括2例正常患者新发病灶),无明显变化10例,略有吸收7例。结论COVID-19肺炎需要核酸检测确诊,CT检查对临床诊断具有指导作用。

Objective To investigate the early clinical and imaging features of patients with new coronavirus disease 2019(COVID-19)。Methods The epidemiologial history,fist einical symptoms,white blood cell and lymphocyte couns,imaging findings were rttpectiely analyzed and 35 patients with clinically confirmed COVID-19 were evaluated from January 22,2020 to February 10,2020.Results Among 35 cases,29 patients(83%)had a history of epidemiology.The white blood cell count decreased by 10 cases and increased by 1 case;the lymphocyte count decreased by 16 cases and incteased by 1 case.34 patients had clinical symptoms,including 34 cases of fever,9 cases of fatigue,myalga,18 cases of dry cough,and 3 cases of sore throat.35 cases of the first CT manifetaion:normal 2 cases,33 cases of pneumonia.The lesion involved 4 cases of umilateral lung and 29 cases of both lungs;30 cases showed patchy ground glass shadow,mainly located under the pleura;2 cases of subpleural cord shadow;Shadow and bronchial inflation sign in 1 case.Chest CT re-examninaion at 3-6 days:18 cases progressed(including 2 new cases of normal patients),10 cases had no obvious changes,and 7 cases were slighdly absorbed.Conclusion The diagnosis of covid-19 pneumonia needs nucleic acid detection.CT examination plays a guiding role in clinical diagnosis.