磁辅助快速血管重建技术在肝移植中的应用

Application of magnetic-assisted rapid vascular reconstruction in liver transplantation

目的探讨磁辅助快速血管重建技术在肝移植中的应用。方法回顾性分析2018年11月—2019年12月之间进行磁辅助快速血管重建及常规缝合重建的肝移植患者临床资料。结果纳入研究的177例肝移植患者中,5例接受磁辅助肝移植,172例患者接受常规肝移植。两组对比,供受者年龄、受者术前Child-Pugh分类、原发疾病以及冷缺血时间无显著性差异(P>0.05)。接受磁辅助肝移植患者无肝期时间为10.3(9.5~13.2)min,明显短于常规肝移植患者43.5(35.8~55.6)min(P<0.001)。但移植术后受者肝转氨酶、总胆红素、血管相关并发症发生率,例如肝动脉、门静脉或下腔静脉血栓形成、胆管狭窄以及急性肾功能不全无显著性差异(P>0.05)。结论使用磁辅助快速血管重建技术在肝移植中是安全可行的,可显著缩短无肝期时间。

Objective To explore the application of magnetic-assisted fast major vascular reconstruction technique in liver transplantation.Methods The clinical data of liver transplant patients undergoing magneticassisted fast major vascular reconstruction and conventional suture reconstruction between November 2018 and December 2019 were retrospectively analyzed.Results A total of five patients were finally enrolled in magneticassisted Liver transplantation(LT),whereas 172 patients underwent regular LT.The donor age,primary disease,as well as the warm and cold ischemia time were comparable between magnetic-assisted and regular LT groups(P>0.05).In addition,the recipient age,sex,primary disease and preoperative Child-Pugh classification were not different,patients undergoing magnetic-assisted LT experienced an median anhepatic period of 10.3(9.5~13.2)min,which was significantly shorter versus 43.5(35.8~55.6)min of patients who underwent regular LT(P<0.001).Of note,postoperative liver transaminase,as well as total bilirubin level were not significantly different at different time stages(P>0.05).In addition,the incidence of vascular associated complications,such as hepatic artery,portal vein or IVC thrombosis,biliary stenosis,as well as acute renal dysfunction were all comparable between the two groups(P>0.05).Conclusion Fast revascularization of the donor liver by using the novel magnetics is safe and feasible in LT.