膀胱恶性外周神经鞘膜瘤一例报告

A case report of malignant peripheral nerve sheath tumors of the bladder

膀胱恶性外周神经鞘膜瘤是一种罕见的恶性肿瘤,常继发于1型神经纤维瘤病(NF-1),少数为散发病例。本文报道1例行经尿道切除的70岁男性膀胱恶性外周神经鞘膜瘤患者,术后辅助吉西他滨膀胱灌注治疗,随访12个月,无局部复发和远处转移。

Malignant peripheral nerve sheath tumors(MPNST)of the bladder is a very rare malignant tumor,usually secondary to neurofibromatosis type 1(NF-1),with a few sporadic cases.This paper reports a case of 70-year-old man with bladder MPNST who underwent transurethral resection.Adjuvant intravesical instillation with gemcitabine was given after surgery,and there was no local recurrence and distant metastasis after 12-month follow-up.This paper also made a corresponding literature review.