冠心病患者中冠脉血管狭窄程度与睡眠呼吸暂停低通气指数及嗜睡的相关性分析

Correlation between Coronary Stenosis and Sleep Apnea Hypoventilation Index and Drowsiness in Patients with Coronary Heart Disease

目的:分析冠心病患者中冠脉血管狭窄程度与睡眠呼吸暂停低通气指数及嗜睡的相关性。方法:择取2017年1月~2018年12月在某院就诊的冠心病冠脉轻度狭窄、中重度狭窄患者各选择50例作为轻度组及中重度组,另选取接受体检且无冠脉狭窄的健康人50例作为对照组,分析3组试验对象睡眠呼吸暂停通气指数与嗜睡情况差异。结果:轻度组、中重度组Gensini评分、每小时AHI次数、ODI3次数、ODI4次数、TG、TC、LDL-C水平、嗜睡率均显著高于对照组(P<0.05),前两组中重度水平更高(P<0.05);轻度组、中重度组HDL-C水平显著低于对照组(P<0.05),其中,中重度组水平更低(P<0.05)。结论:冠心病患者冠脉血管狭窄程度越严重,可能睡眠呼吸暂停低通气指数越高,睡眠指数越严重。

Objective:To analyze correlation between coronary stenosis and sleep apnea hypoventilation index and drowsiness in patients with coronary heart disease.Methods:50 patients with mild coronary stenosis and 50 patients with moderate and severe coronary stenosis from January 2017 to December 2018 were selected as mild group and moderate and severe group,and 50 healthy people without coronary stenosis were selected as control group.The differences of sleep apnea hypoventilation index and drowsiness among the three groups were analyzed.Results:Gensini scores,AHI count,ODI3 count,ODI4 count,TG,TC,LDL-C levels and drowsiness rate in mild group and moderate and severe group were significantly higher than those in control group(P<0.05).The first two groups had higher moderate and severe levels(P<0.05);The HDL-C levels were significantly lower in mild group and moderate and severe group than in control group(P<0.05),and lower in moderate and severe group(P<0.05).Conclusion:The more serious coronary artery stenosis is,the higher the sleep apnea hypoventilation index and the more serious the sleep index is.