抗痨方案包含利福布汀用于治疗艾滋病合并肺结核的疗效分析

Analysis of the Curative Effect of Anti-tuberculosis Program Including Rifabutin in the Treatment of AIDS Complicated with Tuberculosis

目的:探讨抗痨方案包含利福布汀用于治疗艾滋病合并肺结核的疗效。方法:抽取某院2017年5月~2019年12月期间收治的60例艾滋病合并肺结核患者,通过电脑抽签的方式进行分组,对照组常规抗结核治疗联合依非韦伦抗病毒治疗,观察组给予包含利福布汀抗痨治疗联合含依非韦伦抗病毒治疗,对比两组患者治疗效果。结果:观察组病灶吸收率、痰检转阴率、CD4细胞计数增长情况均优于对照组,不良反应率显著低于对照组(P<0.05),有统计学意义。结论:抗痨方案包含利福布汀用于治疗艾滋病合并肺结核疗效显著,能够有效提升肺部病灶吸收率、痰检转阴率,改善CD4细胞计数情况,降低不良反应风险,值得进一步推广研究。

Objective:To explore the efficacy of anti-tuberculosis programs including rifabutin in the treatment of AIDS complicated with tuberculosis.Methods:A total of 60 AIDS patients with tuberculosis in a hospital from May 2017 to December 2019 were selected and randomly divided into two groups.The control group was given conventional anti-tuberculosis treatment+efavirenz antiviral treatment,and the observation group was given rifabutin anti-tuberculosis treatment+efavirenz antiviral treatmen,then the treatment effects of the two groups were compared.Results:The lesion absorption rate,sputum conversion rate,and CD4 cells count growth in the observation group were better than those of the control group,the adverse reaction rate was significantly lower than that of the control group,and the difference was statistically significant(P<0.05).Conclusion:The anti-tuberculosis program including rifabutin in the treatment of AIDS complicated with tuberculosis can effectively increase the absorptionrate of lung lesions,the rate of negative sputum examination,improve the CD4 cell count,and reduce the risk of adverse reactions,which is worthy of further promotion and research.