地屈孕酮对50例宫腔镜下子宫内膜息肉切除术后预防复发的观察

Observation of dydrogesterone in the prevention of recurrence after endometrial polypectomy under hysteroscope in 50 cases

目的:观察宫腔镜下子宫内膜息肉切除术(transcervical resection of polyps,TCRP)后服用地屈孕酮对预防子宫内膜息肉复发的疗效。方法:选取100例行TCRP手术患者根据治疗方法分为观察组组(n=50)与对照组(n=50)。观察组行TCRP手术后给予地屈孕酮3个月经周期的治疗,对照组单纯行TCRP手术。比较术后两组复发率,术前、术后血红蛋白水平及月经量情况。结果:观察组治疗后6个月、12个月复发率均显著低于对照组(P<0.05);治疗后12个月的月经量、月经期天数、月经周期的改善程度均明显好于对照组(P<0.05);血红蛋白含量术后12个月明显高于对照组(P<0.05)。结论:TCRP术后服用地屈孕酮可以有效减少复发率,减少月经出血量,改善血红蛋白。

Objective:To observe the effect of dydrogesterone on preventing recurrence of endometrial polyps after transcervical resection of polyps(TCRP).Methods:One hundred patients undergoing TCRP were divided into an observation group(n=50)and a control group(n=50).The observation group was treated with dydrogesterone for three menstrual cycles after TCRP and the control group with TCRP alone.The postoperative recurrence rate,the hemoglobin levels and the menstrual volume before and after operation were compared.Results:The recurrence rates postoperative 6 and 12 months were significantly lower,the hemoglobin content postoperative 12 months was significantly higher and the improvement in menstrual volume,menstrual period days and menstrual cycle were significantly better in the observation group than the control group(P<0.05).Conclusion:Dydrogesterone can effectively reduce the recurrence rate,menstrual bleeding volume and hemoglobin level after TCRP.