肝硬化脾功能亢进患者部分脾动脉栓塞术后并发症发生的影响因素研究

Study on the influencing factors of complications after partial splenic artery embolization in patients with cirrhosis and hypersplenism

目的:探讨肝硬化脾功能亢进患者部分脾动脉栓塞术后并发症发生的影响因素。方法:回顾性分析我院收治的60例行部分脾动脉栓塞术的肝硬化脾功能亢进患者的临床资料,依据术后是否出现并发症分为研究组(n=11,出现并发症)和对照组(n=49,未出现并发症),分析可能引发部分脾动脉栓塞术后患者并发症发生的影响因素。结果:经logistic多因素分析显示,术中栓塞范围≥60%、术中未抗生素给药、Child-Push评分高、术前脾体积大、梗死脾体积大、脾栓塞比例大、栓塞材料(明胶海绵)、栓塞位置(脾下极动脉)是引发术后并发症发生的危险因素(OR>1,P<0.05)。结论:要针对以上因素,采取有效措施降低并发症发生率。

Objective:To investigate the influencing factors of complications after partial splenic artery embolization in patients with cirrhosis and hypersplenism.Methods:The data from 60 patients with cirrhosis and hypersplenism underwent partial splenic artery embolization were retrospectively analyzed and they were divided into a study group(n=11)and a control group(n=49)based on their postoperative complications.Results:Logistic multivariate analysis showed that risk factors for postoperative complications were involved in intraoperative embolization range≥60%,intraoperative non-antibiotic administration,high Child-Push score,large preoperative splenic volume,large infarct splenic volume,large proportion of splenic embolization,embolization material(gelfoam)and embolization position(inferior splenic polar artery)(OR>1,P<0.05).Conclusion:Effective measures should be taken to reduce the incidence of complications.