糖皮质激素联合茶碱治疗老年哮喘的临床效果

Clinical Effect of Glucocorticoid Combined With Theophylline on Elderly Asthma

目的研究分析针对老年哮喘疾病患者临床中采取糖皮质激素联合茶碱治疗的综合效果。方法筛选出医院于2018年1月—2019年6月期间接收的患有哮喘病的老年患者90例,根据患者的个人意愿的差异性将其随机分成两组,分别在临床中给予糖皮质激素治疗(常规组45例)和糖皮质激素联合茶碱治疗(试验组45例);观察对比两组选择不同治疗模式后的应用疗效。结果两组的临床疗效相对确切,试验组的临床疗效(91.11%)显著优于常规组(73.33%),且试验组的临床不良反应率(4.44%)远小于常规组的17.78%,组间差异均具有统计学意义(P<0.05);试验组患者治疗后的常规指标及肺功能指标均显著优于常规组,组间差异具有统计学意义(P<0.05)。结论糖皮质激素联合茶碱治疗可以有效改善老年哮喘患者的一系列临床不适表现,并且能够逐步增强患者的临床疗效,药物具备较强的安全性与有效性。

Objective To study and analyze the comprehensive effect of glucocorticoid combined with theophylline in clinical treatment for elderly asthma patients.Methods 90 elderly patients with asthma admitted to our hospital from January 2018 to June 2019 were selected,and all patients were randomly divided into two groups according to their own treatment wishes.Glucocorticoid therapy(routine group,45 cases)and glucocorticoid combined with theophylline therapy(experimental group,45 cases)were given in clinic respectively.To observe and compare the overall clinical effect of two groups of patients after adopting different treatment methods.Results The overall therapeutic effect of the two groups of patients was obvious.The total effective rate(91.11%)of the experimental group was significantly better than that of the conventional group(73.33%),and the incidence of adverse reactions after treatment in the experimental group was 4.44%,significantly lower than that of the conventional group(17.78%).There were significant differences between groups(P<0.05).The routine indexes and pulmonary function indexes of the patients in the experimental group after treatment are significantly better than those in the conventional group,with significant differences between the groups(P<0.05).Conclusion Glucocorticoid combined with theophylline treatment can effectively improve the clinical related symptoms of elderly asthma patients,and can also improve the treatment effect of patients as a whole.The drug has strong safety and effectiveness.