摘要
目的探讨干燥综合征(Sj?gren's syndrome,SS)患者颌下腺MRI的表现及诊断效能。材料与方法收集确诊为SS的31例女性患者和15例健康志愿者的颌下腺MRI图像。观察T1WI、T2WI及抑脂T2WI图像,并对患者颌下腺进行脂肪信号分级。测量受试者双侧颌下腺体积,并观察两组体积改变。结果所有患者均呈双侧颌下腺信号不均改变,T1WI和T2WI均为多发弥漫分布脂肪信号,抑脂T2WI呈低信号。在62个腺体中,常规MRI检出病变50个,无假阳性结果。对照组15例30个颌下腺腺体内未见脂肪信号,脂肪信号分级为0级。颌下腺脂肪信号分级的敏感度为80.7%,阳性预测值为100%,特异度为100%。颌下腺脂肪信号分级的曲线下面积(area under curve,AUC)为0.903。病例组颌下腺体积小于对照组体积(P<0.05),病例组非0级颌下腺体积小于0级颌下腺体积(P<0.05)。病例组颌下腺体积与脂肪信号分级相关性较差(r=-0.102,P>0.05),且结果无统计学意义。结论常规颌下腺MRI检查可以作为辅助诊断SS的影像学检查之一。
Objective:To investigate the MRI imaging features and diagnostic efficacy of submandibular glands in patients with Sjogren’s syndrome(SS).Materials and Methods:MRI images of the submandibular glands of 31 patients diagnosed with SS and 15 healthy volunteers were collected.Observed T1 WI,T2 WI and lipid-suppressing T2 WI images,and classified the fat signal of the submandibular glands of the patients.Measured the volume of the bilateral submandibular glands of the subject and observed the volume changes of the two groups.Results:All patients showed uneven changes in bilateral submandibular gland signals.Both T1 WI and T2 WI images showed multiple diffuse fat signals,and lipid-suppressed T2 WI showed low signals.Of the 62 glands,50 lesions were detected by conventional MRI,with no false positive results.There are 12 at grade 0,14 at grade 1,10 at grade 2,13 at grade 3,and 13 at grade 4.There were no fat signals in 30 submandibular glands in 15 cases in the control group,and the fat signal grade was 0.The sensitivity of the submandibular gland was 80.7%,and the positive predictive value was 100%,specificity is 100%.The AUC of submandibular gland fat signal classification is 0.903.The volume of the submandibular gland in the case group was less than that of the control group(P<0.05),and the volume of the non-grade submandibular gland in the case group was less than that of grade 0(P<0.05).The correlation between the volume of submandibular glands and the classification of fat signals in the case group was poor(r=-0.102,P>0.05),and the results were not statistically significant.Conclusions:Routine submandibular gland MRI examination can be used as one of the imaging examinations to diagnose SS.
作者
纪权书
丁长伟
王月
JI Quanshu;DING Changwei;WANG Yue(Department of Radiology,Shengjing Hospital of China Medical University,Shenyang 110004,China)
出处
《磁共振成像》
CAS
2020年第12期1129-1132,共4页
Chinese Journal of Magnetic Resonance Imaging
基金
辽宁省自然科学基金(编号:20170541045)。
关键词
干燥综合征
颌下腺
磁共振成像
Sjogren’s syndrome
submandibular gland
magnetic resonance imaging