大黄牡丹汤保留灌肠治疗湿热瘀结型慢性盆腔炎临床观察

Clinical Observation on Dahuang Mudan Decoction Retention Enema in the Treatment of Chronic Pelvic Inflammatory Disease with Dampness-heat Stasis

目的探讨大黄牡丹汤保留灌肠对湿热瘀结型慢性盆腔炎患者的临床疗效。方法前瞻性选择2018年12月—2019年7月湿热瘀结型慢性盆腔炎患者58例,随机分为2组,对照组29例采用甲硝唑联合左氧氟沙星片口服治疗;观察组29例采用大黄牡丹汤保留灌肠,持续治疗2周。评价患者的治疗效果,比较中医证候积分。结果2组患者干预后下腹痛、带下黄、苔黄腻评分降低;观察组患者干预后下腹痛、带下黄、苔黄腻评分低于对照组,差异有统计学意义(P<0.05);治疗组总有效率为96.55%高于对照组总有效率为79.31%,差异有统计学意义(P<0.05)。结论大黄牡丹汤保留灌肠治疗慢性盆腔炎湿热瘀结型时,可缓解下腹疼痛,改善临床症状,发挥清热化瘀、止痛利湿作用,有较好的的临床效果,值得临床推广应用。

Objective To investigate the clinical effect of Dahuang Mudan decoction retention enema in the treatment of chronic pelvic inflammatory disease with dampness-heat stasis.Methods From December 2018 to July 2019,58 patients with chronic pelvic inflammatory disease with dampness-heat stasis were selected and randomly divided into 2 groups.In the control group,29 patients were treated with metronidazole combined with levofloxacin orally.In the observation group,29 patients received Dahuang Mudan decoction retention enema for 2 weeks.Results The therapeutic effect of patients was evaluated and the TCM syndrome scores were compared.After intervention,the scores of lower abdominal pain and yellow with moss decreased in 2 groups.After intervention,scores of lower abdominal pain and yellow with moss in the observation group were lower than those in the control group,and the difference was statistically significant(P<0.05).The total effective rate of the treatment group was 96.55%,which was higher than that of the control group(79.31%),and there had statistically significant difference(P<0.05).Conclusion Dahuang Mudan decoction retention enema in the treatment of chronic pelvic inflammatory disease with dampness-heat stasis can relieve lower abdominal pain,improve clinical symptoms,and play a role in clearing heat and removing blood stasis,relieving pain and dampness.