米非司酮在子宫腺肌病治疗中的临床效果及不良反应分析

Analysis of Clinical Effects and Adverse Reactions of Mifepristone in the Treatment of Adenomyosis

目的探讨子宫腺肌病患者选用米非司酮治疗的价值。方法选取2018年5月至2019年4月济宁市嘉祥县人民医院收治的118例子宫腺肌病患者作为研究对象,按照随机信封法分为两组,对照组58例选用常规方案治疗,观察组60例选用米非司酮治疗,统计对比两组患者的临床总有效率、不良反应发生率、临床指标。结果观察组患者的临床总有效率(98.33%)高于对照组(87.93%),观察组患者不良反应发生率(7.50%)低于对照组(15.00%),观察组患者临床指标优于对照组,以上差异具有统计学意义(P<0.05)。结论将米非司酮应用在子宫腺肌病治疗中可提高临床疗效,降低不良反应发生率,效果理想。

Objective To explore the value of mifepristone in patients with adenomyosis.Methods A total of 118 cases of adenomyosis from May 2018 to April 2019 in Jining Jiaxiang County People's Hospital were selected,they were divided into two groups(random envelope method).In the control group,58 patients were treated with routine regimen.In observation group,60 cases were treated with mifepristone.The total clinical efficiency,incidence of adverse reactions and clinical indexes were compared.Results The total effective rate in the observation group(98.33%)was higher than that in the control group(87.93%),incidence of adverse reactions in the observation group(7.50%)was lower than the control group(15.00%),clinical indexes of the observation group were better than those of the control group,above difference has statistical significance(P<0.05).Conclusion The application of mifepristone in the treatment of adenomyosis can improve the clinical effect and reduce the incidence of adverse reactions.