内镜下硬化剂注射术及套扎术治疗Ⅱ度内痔的临床研究

Endoscopic sclerotherapy and ligation for the treatment of grade II internal hemorrhoids

目的通过比较内镜下硬化剂注射术及套扎术治疗Ⅱ度内痔的临床疗效及安全性,从而为临床上Ⅱ度内痔治疗方案的选择提供指导意见。方法回顾性分析2019年1月至2020年7月期间,于保定市第一中心医院行内镜下硬化剂注射术或套扎术治疗的Ⅱ度内痔患者的临床资料,按照内镜下术式的不同,将纳入的患者分为硬化组和套扎组,比较两组患者临床疗效及术后并发症发生情况的差异。结果共纳入患者35例,其中硬化组27例、套扎组8例。临床疗效方面:硬化组中,痊愈14例、好转10例、无效3例,痊愈率51.85%,治疗有效率为88.89%;套扎组中,痊愈6例、好转2例,痊愈率75%,治疗有效率为100%;两组患者痊愈率及治疗有效率的差异均无统计学意义(P>0.05)。术后并发症方面:硬化组术后并发症发生率为11.11%(3/27),其中1例出现肛门疼痛和发热,1例出现肛门疼痛,1例出现少量便血;套扎组术后并发症发生率为25%(2/8),其中1例出现肛门疼痛和便血,1例出现肛门疼痛。两组患者术后并发症发生情况的差异无统计学意义(P>0.05)。结论内镜下硬化剂注射术与套扎术治疗Ⅱ度内痔均具有较好的临床疗效,有待大样本研究进一步证实。

Objective Compare the clinical efficacy and safety of endoscopic sclerotherapy and ligation for the treatment of grade II internal hemorrhoids,and provide guidance for the choice of treatment.Methods Clinical data of grade II internal hemorrhoids patients,underwent endoscopic sclerotherapy or ligation in No.1 central hospital of Baoding from Jan 2019to Jul 2020,were retrospectively analyzed.Clinical efficacy and postoperative complications of the two groups were compared.Results A total of 35 patients were included,with 27 cases in the sclerosis group and 8 cases in the ligation group.In terms of clinical efficacy:14 patients cured,10 patients improved and 3 patients were ineffective in the sclerosis group.The cured rate was 51.85%and the effective rate was 88.89%in the sclerosis group.6 patients cured,2 improved in the ligation group.The cured rate was 75.00%,and the effective rate was 100%in the ligation group.There was no significant difference in cured or effective ratio between the two groups(P>0.05).In terms of postoperative complications:the incidence of postoperative complications was 11.11%(3/27)in the sclerosis group and 25%(2/8)in the ligation group.There was no significant difference in complications between the two groups(11.11%vs 25%,P>0.05).Conclusions Both endoscopic sclerotherapy and endoscopic ligation obtained satisfying clinical effect in the treatment of grade II internal hemorrhoids,while further research with large sample data is needed.