335例炎症性肠病患者的临床特点分析

Clinical characteristics of 335 patients of inflammatory bowel disease

目的:总结炎症性肠病(IBD)的临床特点。方法:回顾性收集浙江中医药大学附属第一医院2013年7月至2018年7月期间确诊为IBD的患者,分析患者的人口学资料和临床资料。结果:共纳入335例IBD,其中溃疡性结肠炎(UC)151例,克罗恩病(CD)184例。UC平均患病年龄大于CD[(45.50±15.40)岁比(36.15±13.48)岁,P<0.001];UC腹泻、黏液脓血便多见(P均<0.001),而CD腹痛、肛瘘和肛周脓肿多于UC(P均<0.05)。结论:CD患病年龄早于UC。UC腹泻、黏液脓血便多见,而CD以腹痛、肛瘘和肛周脓肿更为多见。对于临床疑诊者应常规行内镜,尤其胃镜检查,以防漏诊。

Objective To summarize the clinical features of patients with inflammatory bowel disease(IBD).Methods Clinical data of patients diagnosed as IBD in the First Affiliated Hospital,Zhejiang University of Traditional Chinese Medicine from July 2013 to July 2018 were retrospectively analyzed.Results Of 335 IBD patients,151 were diagnosed as ulcerative colitis(UC)and 184 were Crohn′s disease(CD).The average age of UC was higher than that of CD[(45.50±15.40)years vs.(36.15±13.48)years,P<0.001].Diarrhea,mucopurulence and bloody stool were more common in UC patients(all P<0.001),while abdominal pain,anal fistula and perianal abscess were significantly increased in CD patients(all P<0.001).Conclusions The age of CD was earlier than that of UC.Diarrhea,mucopurulent and bloody stool were more common in UC,and abdominal pain,anal fistula and perianal abscess were more common in CD.Patients suspected of CD should be routinely examined by endoscopy,especially gastroscopy,to prevent missed diagnosis.