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即刻负重与非即刻负重预后对比的Meta分析

Comparison between outcomes of immediate loading and non-immediate loading implants:A Meta-analysis
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摘要 目的汇总目前对比即刻负重与非即刻负重的临床研究结论,进而判断即刻负重的疗效是否可预期,并分析其是否可以满足临床需求以及潜在的影响因素,从而指导下一步的临床研究。方法检索回顾外文数据库中截至2018年12月的相关临床研究文献,并汇总最终获取的文献中即刻负重与非即刻负重的种植体相关临床指标(边缘骨吸收及其改变、ISQ、种植体存留率),建立数据库并进行Meta分析。结果检索数据库并进行筛查后,最终纳入了32篇文献进行分析,在边缘骨吸收及其改变、ISQ、种植体存留率(基于患者或种植体)这5个指标上,即刻负重可达到与非即刻负重相近的的临床效果。结论在身体健康、全身状况良好、无系统性疾病的缺牙患者中,应用即刻负重的修复方案疗效是可预期的,其预后与非即刻负重无统计学差异。 Objective To summarize clinical outcomes of immediate loading and non⁃immediate loading,judging that whether the outcome of immediate loading implants can be expected,and whether it can satisfy clinical demand and potential influencing factors,giving suggestions to further clinical trials.Methods Our study searched foreign database for relevant articles up to December 2018,and collected clinical parameters of immediate and non⁃immediate loading implants including marginal bone loss,marginal bone loss change,implant stability quotient and survival rate of implants,established database to perform Meta⁃analysis.Results Finally,32 studies were included in the analysis.As for marginal bone loss,marginal bone loss change,implant stability quotient and survival rate of implants,there was no significant difference between clinical outcomes of immediate loading and non⁃immediate loading.Conclusion It is shown that there is no significant difference between immediate loading and non⁃immediate loading for implant resto⁃ration on patients without systematic diseases,and the outcome of immediate loading implant is expectable.
作者 赵国强 刘益 张思佳 宋应亮 ZHAO Guoqiang;LIU Yi;ZHANG Sijia;SONG Yingliang(State Key Laboratory of Military Stomatology&National Clinical Research Center for Oral Diseases&Shaanxi Engineering Research Center for Dental Materials and Advanced Manufacture,Department of Oral Implantology,School of Stomatology,The Fourth Military Medical University,Xi'an 710032,China)
出处 《口腔医学》 CAS 2020年第11期998-1004,1036,共8页 Stomatology
基金 国家自然科学基金面上项目(81771107)。
关键词 口腔种植 即刻负重 边缘骨吸收 种植体存留率 META分析 oral implant immediate loading marginal bone loss survival rate of implants Meta analysis
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