医护人员体检血液学指标随访变化及危险因素分析

An Analysis on the Follow-up Changes and Risk Factors of Blood Indexes in Physical Examination of Medical Staff

目的通过同单位体检人员血液指标的跨年对比分析,研究该人群慢性指标的迁延趋势,探讨健康管理方案。方法收集2014年和2018年同单位体检人员血清癌胚抗原(CEA)、甲胎蛋白(AFP)、葡萄糖(GLU)、三酰甘油(TG)、总胆固醇(CHOL)、尿酸(UA)等指标检测结果,进行回顾性分析。结果以2014年为标准,2018年CEA、GLU、CHOL呈下降趋势;TG、UA呈上升趋势,各指标差异均具有统计学意义(P<0.05)。以年次分组,CEA、GLU、TG、CHOL、UA各指标两年差异具有统计学意义(P<0.05);除外AFP(P=0.158);CEA、GLU、CHOL、UA两年异常率差异具有统计学意义(P<0.05),除外AFP、TG(P=0.471,P=0.085)。以性别分组,2014年CEA、AFP、GLU、TG、CHOL、UA各指标男女差异具有统计学意义(P<0.05);2018年CEA、AFP、GLU、TG、CHOL、UA各指标男女差异具有统计学意义(P<0.05)。以年龄分组,CEA、AFP、GLU、TG、CHOL、UA在不同年龄段差异具有统计学意义(P<0.05)。体检人员CEA异常升高相关指标包括年龄、性别、GLU、TG、UA(P<0.05)。结论对于规律性单位体检,应在个体报告的基础上,规范化进行总体数据的年度汇总,定期累积,探讨慢性指标的发展趋势及相关性,对无症状的指标异常进行早期有效干预,促进体检大数据的健康管理。

Objective To study the trend of chronic indexes and health management plan by comparing the blood indexes of the same physical examination personnel over the years.Methods The data of serum carcinoembryonic antigen(CEA),alpha-fetoprotein(AFP),glucose(GLU),triglyceride(TG),total cholesterol(CHOL),and uric acid(UA)were collected and analyzed retrospectively from 2014 to 2018.Results CEA,GLU and CHOL showed a downward trend,while TG and UA showed an upward trend in 2018 compared with results of 2014(P<0.05).CEA,GLU,TG,CHOL and UA were significantly different between two years(P<0.05),except for AFP(P=0.158).CEA,GLU,CHOL and UA were significantly different between two years(P<0.05),except for AFP and TG(P=0.471,P=0.085).CEA,AFP,GLU,TG,CHOL and UA were significantly different between male and female in 2014 and 2018,respectively(P<0.05).CEA,AFP,GLU,TG,CHOL and UA were significantly different among different age groups(P<0.05).The relevant indexes of CEA abnormal increase in physical examination personnel included age,sex,GLU,TG and UA(P<0.05).Conclusion For the regular physical examination,we should standardize the collection process of general data on the basis of individual reports,accumulate data regularly,and discuss the development trend and correlation of chronic indicators timely.We should carry on the early effective intervention to the symptom-free index abnormality in order to promote the health management of the physical examination data.