子宫动脉栓塞术在剖宫产瘢痕部位妊娠中的治疗效果及对不良反应发生率的影响

Effect of Uterine Artery Embolization in Cesarean Scar Pregnancy and Its Influence on the Incidence of Adverse Reactions

目的:探讨子宫动脉栓塞术在剖宫产瘢痕部位妊娠中的治疗效果及对不良反应发生率的影响。方法:选取2016年2月-2020年2月收治的剖宫产瘢痕部位妊娠患者97例,按照奇偶数字将其分为两组,对照组(n=48)和研究组(n=49)。对照组给予药物联合B超监测下清宫术进行治疗,研究组给予子宫动脉栓塞术联合B超监测下清宫术进行治疗。比较两组患者的临床治疗成功率、不良反应与并发症发生率、临床指标及治疗前后患者卵巢功能。结果:研究组患者的临床治疗成功率高于对照组,差异有统计学意义(P<0.05)。两组不良反应与并发症发生率比较,差异均无统计学意义(P>0.05)。研究组患者的临床指标明显均优于对照组,差异均有统计学意义(P<0.05)。治疗后,研究组的FSH、E2、LH、T与治疗前比较,差异均无统计学意义(P>0.05),对照组的FSH、E2、LH、T与治疗前比较,差异均有统计学意义(P<0.05)。结论:对剖宫产瘢痕部位妊娠患者实施子宫动脉栓塞术联合B超监测下清宫术进行治疗,其治疗效果更突出,且安全性较高,术后住院时间更短,出血量更少,能减少患者的经济负担,对卵巢功能影响不明显,不会影响患者的再次妊娠。

Objective:To investigate the effect of uterine artery embolization on cesarean scar pregnancy and the incidence of adverse reactions.Method:A total of 97 patients with uterine scar pregnancy from February 2016 to February 2020 were selected,they were divided into two groups according to the odd and even Numbers,the control group(n=48)and the study group(n=49).The control group was given drugs combined with B-ultrasound monitoring of uterine curettage,the study group was treated with uterine artery embolization combined with B-ultrasound monitoring of uterine curettage.The success rate of clinical treatment,incidence of adverse reactions and complications,clinical indicators,and ovarian function of patients before and after treatment were compared between the two groups.The control group was given medicine combined with curettage under B-ultrasound monitoring,while the study group was given uterine artery embolization combined with curettage under B-ultrasound monitoring.The clinical treatment success rate,incidence of adverse reactions and complications,clinical indicators and ovarian function before and after treatment were compared between the two groups.Result:The success rate of clinical treatment in the study group was higher than that in the control group,the difference was statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions and complications between the two groups(P>0.05).The clinical indicators of patients in the study group were significantly better than those in the control group,the differences were statistically significant(P<0.05).After treatment,FSH,E2,LH and T in the study group were not significantly different from those before treatment(P>0.05),while FSH,E2,LH and T in the control group were significantly different from those before treatment(P<0.05).Conclusion:Uterine artery embolization combined with B-ultrasound monitoring of uterine curettage was performed in caesarean scar pregnancy,the therapeutic effect was more prominent,the safety was higher,the hospital stay time was short,and the amount of bleeding was less,it can reduce the economic burden of the patients,has no obvious influence on the ovarian function,will not affect the patients’next pregnancy.