腹腔镜与阴式子宫肌瘤剔除术的临床效果及对性激素水平的影响研究

Study on the Clinical Effect of Laparoscopic and Vaginal Myomectomy and Influence for Sex Hormone Levels

目的:研究腹腔镜与阴式子宫肌瘤剔除术的临床效果及对性激素水平的影响。方法:选取2017年1月-2019年12月本院的88例子宫肌瘤患者为研究对象,根据手术方式不同分为A组(腹腔镜子宫肌瘤剔除术)和B组(阴式子宫肌瘤剔除术),各44例。比较两组的手术指标、并发症发生情况、手术前后的生活质量及性激素水平。结果:B组术中出血量少于A组,手术时间及排气时间均短于A组,差异均有统计学意义(P<0.05);而两组住院时间比较,差异无统计学意义(P>0.05)。两组各项并发症发生率比较,差异均无统计学意义(P>0.05)。术后1、4周,两组的WHOQOL-BREF量表各项评分比较,差异均无统计学意义(P>0.05)。术后1、3个月,两组的FSH、LH及E2水平比较,差异均无统计学意义(P>0.05)。结论:阴式子宫肌瘤剔除术在出血量、手术时间及胃肠功能恢复时间方面更具有优势,两类手术方式对性激素及生活质量的影响均较小,且恢复均较快。

Objective:To study the clinical effect of laparoscopic and vaginal myomectomy and influence for sex hormone levels.Method:A total of 88 patients with uterine fibroids in our hospital from January 2017 to December 2019 were selected as the research objects,according to different surgical methods,they were divided into group A(laparoscopic myomectomy)and group B(vaginal myomectomy),44 cases in each group.Operation indexes,occurrence of complications,quality of life and sex hormone levels before and after operation were compared between the two groups.Result:The intraoperative blood loss in group B was less than that in group A,the operative time and exhaust time were shorter than those in group A,with statistically significant differences(P<0.05);however,there was no significant difference in hospital stays between the two groups(P>0.05).There were no statistically significant differences in the incidence of various complications between the two groups(P>0.05).1 and 4 weeks after surgery,there were no statistically significant differences between the two groups in all WHOQOL-BREF scores(P>0.05).1 and 3 months after surgery,there were no statistically significant differences in FSH,LH and E2 levels of the two groups(P>0.05).Conclusion:The vaginal myomectomy has more advantages in blood loss,operation time and recovery time of gastrointestinal function,the influence of the two operations for sex hormone and life quality have little effect,they recover fast.