重复经颅磁刺激联合知行分析疗法治疗抑郁症的效果研究

Effect of Repetitive Transcranial Magnetic Stimulation Combined with Knowledge and Practice Analysis Therapy in the Treatment of Depression

目的:探讨重复经颅磁刺激联合知行分析疗法治疗抑郁症的效果。方法:选取2019年1月-2020年1月本院收治的70例抑郁症患者,按随机数字表法将其分为对照组与观察组,各35例。对照组进行重复经颅磁刺激联合心理健康教育治疗,观察组进行重复经颅磁刺激联合知行分析疗法治疗。比较两组抑郁症状评分、病耻感评分、治疗依从性、认知功能及临床疗效。结果:观察组治疗8周后的汉密尔顿抑郁量表24项版(HAMD-24)评分低于对照组(P<0.05)。观察组治疗8周后的治疗、能力、社交评分及病耻感评估量表总分均低于对照组(P<0.05)。治疗8周后,观察组中依从性好者的占比高于对照组(P<0.05)。观察组治疗8周后的完成分类数、持续错误数、随机错误数、正确应答数及总应答数均优于对照组(P<0.05)。观察组治疗总有效率为97.14%,高于对照组的77.14%(P<0.05)。结论:重复经颅磁刺激联合知行分析疗法能有效减轻抑郁症患者抑郁症状和病耻感,提升患者的认知情况、治疗依从性和临床疗效,具有临床推广价值。

Objective:To explore the effect of repetitive transcranial magnetic stimulation combined with knowledge and practice analysis therapy in the treatment of depression.Method:A total of 70 patients with depression admitted to our hospital from January 2019 to January 2020 were selected and divided into control group and observation group according to random number table method,35 patients in each group.The control group was treated with repetitive transcranial magnetic stimulation combined with mental health education,and the observation group was treated with repetitive transcranial magnetic stimulation combined with knowledge and practice analysis therapy.Depressive symptom scores,stigma scores,treatment compliance,cognitive function and clinical efficacy were compared between the two groups.Result:The 24 item version of Hamilton depression scale (HAMD-24) score of the observation group after 8 weeks of treatment was lower than that of the control group (P<0.05).Treatment,ability,social scores and total score of stigma assessment scale of the observation group after 8 weeks of treatment were lower than those of the control group (P<0.05).After 8 weeks of treatment,the proportion of good compliance of the observation group was higher than that of the control group (P<0.05).The number of completed classification,continuous error,random error,correct response and total response in the observation group after 8 weeks of treatment were better than those in the control group (P<0.05).The total effective rate of treatment in the observation group was 97.14%,it was higher than 77.14% in the control group (P<0.05).Conclusion:Repetitive transcranial magnetic stimulation combined with knowledge and practice analysis therapy in the treatment of depression patients can effectively reduce the symptoms of depression and stigma,and improve the cognitive status,treatment compliance and clinical efficacy of patients,which is worthy of clinical promotion.