间歇性禁食、肠道菌群与非酒精性脂肪肝相关性研究进展

Research Progress on Relationship between Intermittent Fasting,Gut Microbiota and Non-alcoholic Fatty Liver

随着多组学技术的发展,肠道菌群与机体之间的关系不断被证实.肠道菌群动态平衡被打破,发生肠道菌群失调,从而引起非酒精性脂肪肝的发生发展.间歇性禁食可重塑肠道菌群,改善肥胖、Ⅱ型糖尿病等疾病.文章通过论述间歇性禁食、肠道菌群与非酒精性脂肪肝之间的关系,以期为非酒精性脂肪性肝病的临床研究提供参考依据.

With the development of multi-group technology,the relationship between gut microbiota and organism has been continuously confirmed.The dynamic balance of gut microbiota is broken,and the imbalance of gut microbiota occurs,which leads to the occurrence and development of non-alcoholic fatty liver.Intermittent fasting can reshape gut microbiota and improve diseases such as obesity and type 2 diabetes.This paper discussed the relationship between intermittent fasting,gut microbiota and non-alcoholic fatty liver disease,in order to provide more directions for the clinical research of non-alcoholic fatty liver disease.