江苏省盐城市2008—2018年消化道肿瘤死亡情况及其变化趋势分析

Analysis of mortality and their changing trends of gastrointestinal cancer in Yancheng city,Jiangsu province from 2008 to 2018

目的分析江苏省盐城市消化道肿瘤流行特征,评价近年来消化道肿瘤防控效果,为进一步制定消化道肿瘤防控措施提供依据。方法收集2008年1月—2018年12月盐城市全人群死因监测数据及人口资料,应用WHO推荐方法计算消化道肿瘤粗死亡率、标化死亡率、早死概率、年度变化百分比(Annual percentage changes,APC)等指标。结果2008—2018年盐城市食管癌、胃癌和结直肠癌粗死亡率分别为19.00/10万、18.10/10万和4.22/10万,占癌症总死亡的41.32%。食管癌粗死亡率、标化率和早死概率均呈下降趋势(APC分别为-1.49%、-4.97%和-6.39%,P<0.01);胃癌粗死亡率、标化率和早死概率也均呈下降趋势(APC分别为-2.47%、-5.64%、-6.11%,P<0.01);结直肠癌粗死亡率有上升趋势(APC=6.18%,P<0.01),男性标化率和早死概率有上升趋势(APC分别为4.08%、5.02%,P<0.01),女性标化率和早死概率变化无统计学意义(P>0.05)。结论2008—2018年盐城市消化道肿瘤死亡率较高,胃癌、食管癌死亡呈下降趋势,男性结直肠癌有明显上升趋势,应进一步加强早诊早治等综合性防控措施。

Objective The aim of this study was to analyze the epidemiological characteristics of gastrointestinal tumors in Yancheng city,Jiangsu province,evaluate the effect of gastrointestinal tumor prevention and control in recent years,and provide a basis for further development of gastrointestinal tumor prevention and control measures.Methods The whole population of Yancheng city′s death cause monitoring data and population data were collected from 2008 to 2018.The crude mortality of gastrointestinal tumors,standardized mortality,early death probability,annual percentage changes(APC)and other indicators were calculated by WHO recommended methods.Results From 2008 to 2018,the crude mortalities of esophageal cancer,stomach cancer and colorectal cancer were 19.00/100,000,18.10/100,000 and 4.22/100,000,respectively,accounting for 41.32%of total cancer deaths.The crude mortality,standardized mortality and early mortality of esophageal cancer showed a downward trend(APC=-1.49%,-4.97%,-6.39%,P<0.01);the crude mortality,standardized mortality,and early mortality of stomach cancer also had downward trend(APC=-2.47%,-5.64%,-6.11%,P<0.01).The crude mortality of colorectal cancer had an upward trend(APC=6.18,P<0.01).The male standardized mortality and early mortality of colorectal cancer had upward trend(APC=4.08%,5.02%,P<0.01),and there was no statistically change in the female for standardized mortality and early mortality(P>0.05).Conclusion The mortality of gastrointestinal tumors in Yancheng city from 2008 to 2018 was relatively high.The deaths of stomach cancer and esophageal cancer show a downward trend,and male colorectal cancer shows a significant upward trend.Comprehensive prevention and control measures such as early diagnosis and treatment should be further strengthened.