超敏C-反应蛋白和血常规检测在儿童不同呼吸道病原体感染疾病中的诊断价值研究

The diagnostic value of high-sensitivity C-reactive protein and blood routine detection in children with different respiratory pathogens

目的探究超敏C-反应蛋白(hs-CRP)与血常规检测在儿童细菌性感染、病毒性感染及支原体感染中的临床诊断价值。方法选取2018年2月-2019年2月来本院治疗的患者呼吸道感染性疾病儿童128例作为实验组,128例健康体检儿童为对照组,对2组儿童进行hs-CRP和血常规检测。结果细菌性感染组和病毒性感染组中hs-CRP、WBC水平均高于对照组(P <0.05),hs-CRP、WBC的阳性率均高于对照组(P <0.05);细菌性感染组、病毒性感染组及支原体感染组的hs-CRP阳性率分别为78.57%、13.85%和47.62%,WBC的阳性率分别为66.67%、10.77%和28.57%。hs-CRP和WBC联合检测细菌性感染、病毒性感染及支原体感染的阳性率分别为90.48%、29.23%和76.19%,阳性率显著高于hs-CRP或WBC的单项检测率(P <0.05)。结论对儿童进行hs-CRP和血常规的联合检验,可有效提高儿童细菌性感染、病毒性感染和支原体感染的临床检出率,具有一定的临床意义。

Objective To explore the clinical diagnostic value of high-sensitivity C-reactive protein(hs-CRP)and blood routine test in children with bacterial,viral and mycoplasma infection.Methods A total of 128 children with respiratory infec-tious diseases treated in our hospital from February 2018 to February 2019 were selected as the experimental group and 128 healthy children as the control group.Hs-CRP and blood routine tests were carried out in the two groups.Results Statistical results showed that the levels of hs-CRP and WBC in bacterial infection group and viral infection group were higher than those in the control group(P<0.05).The positive rates of hs-CRP and WBC in viral infection group were higher than those in the control group(P<0.05).The levels of hs-CRP and WBC in viral infection group were different from those in the control group(P<0.05).The positive rates of hs-CRP in bacterial infection group,viral infection group and mycoplasma infection group were respectively 78.57%,13.85%and 47.62%.The positive rates of WBC were respectively 66.67%,10.77%and 28.57%.The positive rates of bacterial infection,viral infection and mycoplasma infection detected by hs-CRP and WBC were respectively 90.48%,29.23%and 76.19%.The positive rate was significantly higher than the single detection rate of hs-CRP or WBC(P<0.05).Conclusion The combined detection of hs-CRP and blood routine in children effectively reduce and improve the clinical detection rate of bacterial,viral and mycoplasma infections in children,which is with certain clinical significance.