急诊介入联合替格瑞洛治疗急性心肌梗死临床疗效观察

Observation on the clinical effect of emergency intervention combined with ticagrelor in the treatment of acute myocardial infarction

目的:分析急诊介入联合替格瑞洛治疗急性心肌梗死的临床疗效。方法:2018年2月-2020年2月收治急性心肌梗死患者120例,随机分为两组,各60例。试验组实施急诊PCI联合替格瑞洛治疗;对照组实施急诊PCI联合氯吡格雷治疗。比较两组治疗效果。结果:试验组治疗后左心射血分数、收缩末径、TMP分级、TIMI分级及血浆心肌损伤因子水平均显著优于对照组,差异有统计学意义(P<0.05);试验组无复流发生率显著低于对照组,差异有统计学意义(P<0.05)。结论:急诊介入联合替格瑞洛治疗急性心肌梗死,有较好的治疗效果。

Objective:To analyze the clinical effect of emergency intervention combined with ticagrelor in the treatment of acute myocardial infarction.Methods:From February 2018 to February 2020,120 cases of patients with acute myocardial infarction were enrolled,they were randomly divided into two groups with 60 cases in each group.The experimental group was treated with emergency PCI combined with ticagrelor,while the control group was treated with emergency PCI combined with clopidogrel.The therapeutic effects between the two groups was compared.Results:After treatment,the left ventricular ejection fraction,systolic end diameter,TMP grade,TIMI grade and plasma myocardial injury factor levels in the experimental group were significantly better than those of the control group,the differences were statistically significant(P<0.05).The incidence rate of no reflow in the experimental group was significantly lower than that in the control group,the difference was statistically significant(P<0.05).Conclusion:Emergency intervention combined with ticagrelor in the treatment of acute myocardial infarction has a better therapeutic effect.