酸枣仁汤治疗持续性姿势-知觉性头晕临床研究

Clinical Study on Sour Jujube Decoction in the Treatment Persistent Postural-Perceptual Dizziness

目的:观察酸枣仁汤治疗持续性姿势-知觉性头晕(persistent postural-perceptual dizziness,PPPD)的临床疗效。方法:将66例PPPD患者按照随机数字表法分为观察组和对照组,每组各33例。对照组给予盐酸舍曲林片治疗,观察组在对照组的基础上给予酸枣仁汤治疗。比较两组患者的临床疗效及治疗前后汉密尔顿焦虑量表(milton Anxiety Scale,HAMA)、躯体症状分类量表(somatic symptoms scale,SSRC)、匹茨堡睡眠质量指数量表(pittsburgh sleep quality index scale,PSQI)评分的变化情况。结果:对照组有效率为69.70%,观察组有效率为90.91%,两组患者有效率比较,差异具有统计学意义(P<0.05)。两组患者治疗后HAMA评分、SSRC评分、PSQI评分均低于本组治疗前,且观察组治疗后低于对照组治疗后,差异具有统计学意义(P<0.05)。结论:酸枣仁汤治疗PPPD,在缓解患者头晕症状的同时,还能改善躯体症状、睡眠质量以及焦虑情绪。

Objective:To observe the clinical curative effect of Sour Jujube Decoction on persistent postural-perceptual dizziness(PPPD).Methods:A total of 66 patients with PPPD were randomly divided into observation group and control group,33 cases in each group.The control group was given Sertraline Hydrochloride Tablets,and the observation group was additionally given Sour Jujube Decoction on the basis of the control group.The clinical efficacy and the changes of the scores of Hamilton Anxiety Scale(HAMA),physical symptoms scale(SSRC)and Pittsburgh sleep quality index scale(PSQI)were compared between the two groups before and after the treatment.Results:The effective rate of the control group was 69.7%,and that of the observation group was 90.91%.The difference was statistically significant(P<0.05).HAMA,SSRC,PSQI scores of the two groups after the treatment were lower than those of the same group before the treatment,and the above indexes of the observation group were lower than those of the control group after the treatment,and all the differences were statistically significant(P<0.05).Conclusion:In terms of PPPD,Sour Jujube Decoction can not only relieve dizziness,but also improve physical symptoms,sleep quality and anxiety of the patients.