血清LP-PLA2、CyPA与急性脑梗死后抑郁的相关性研究被引量：1

Relationship between Serum LP-PLA2, CyPA and Depression after Acute Cerebral Infarction

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摘要脑卒中是一种急性脑血管病,包括缺血性卒中和出血性卒中。目前卒中相关死亡人数在逐年增加,而脑梗死在其中更为常见。梗死后抑郁(post-stroke depression,PSD)是主要的并发症之一,严重影响患者卒中后神经功能的恢复及回归社会的能力,增加致残率、死亡率和卒中复发率,尽管预防和治疗取得了进展,但其仍然是影响患者和家庭生活的严重疾病问题,有研究表明,炎性反应在脑梗死后抑郁症病理过程中发挥着重要作用。本文对脂蛋白相关磷脂酶A2、亲环素A与急性脑梗死后抑郁相关性的研究进展进行阐述。 Stroke is an acute cerebrovascular disease, which includes ischemic stroke and hemorrhagic stroke. The number of stroke-related deaths is increasing year by year, and cerebral infarction is more common. Post-stroke depression is one of the major complications, which seriously affects the recovery of neural function and the ability to return to society after stroke, and increases the rate of disability, mortality and recurrence of stroke despite progress in prevention and treatment, however, it is still a serious disease problem that affects patients and family life. Some studies show that inflammatory reaction plays an important role in the pathological process of post-infarction depression. This article reviews the research progress of the relationship between lipoprotein-associated phospholipase A2, Cyclophilin A and post-infarction depression.

作者刘唱和梅 Liu Chang;He Mei(Jiamusi University,Jiamusi 154000;The First Affiliated Hospital of Jiamusi University,Jiamusi 154000,China)

机构地区佳木斯大学佳木斯大学附属第一医院

出处《广东化工》 CAS 2020年第21期76-77,共2页 Guangdong Chemical Industry

关键词脂蛋白相关磷脂酶A2 亲环素A 急性脑梗死后抑郁 lipoprotein-associated phospholipase A2 Cyclophilin A post-stroke depression

分类号 R743.33 [医药卫生—神经病学与精神病学] R446.1 [医药卫生—诊断学]

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1詹青,王丽晶.急性缺血性脑卒中早期康复的时机与策略[J].神经病学与神经康复学杂志,2016,12(1):1-7. 被引量：28
2夏文翠,胡中扬,宋治.脂蛋白相关磷脂酶A2与缺血性脑卒中相关性的Meta分析[J].中南大学学报（医学版）,2017,42(2):208-214. 被引量：12
3崔建美,王宇,王燕,王培育,刘艳艳,杨永清.Cyclophilin A的功能研究进展[J].免疫学杂志,2006,22(z1):47-50. 被引量：1

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