环乳晕切口手术在乳腺癌患者中的应用效果

Circum-areola incision application effect in breast cancer patients

目的探讨环乳晕切口手术在乳腺癌患者中的应用效果。方法采用随机数字表将140例乳腺癌患者分为环切口组和对照组,每组70例,环切口组患者接受环乳晕切口手术治疗,对照组患者接受肿块表面切口手术治疗。比较两组患者的手术相关指标,包括手术时间、腋窝拔管时间、腋窝引流时间;采用简明健康状态调查表(SF-36)比较两组患者的生存质量;比较两组患者的复发情况和并发症发生情况。结果环切口组患者的腋窝拔管时间、腋窝引流时间均短于对照组患者,手术时间长于对照组患者,差异均有统计学意义(P﹤0.05)。术后6个月,两组患者的生理功能、社会功能、生理职能、精神健康、活力、情感职能和总体健康评分均高于本组术前,且环切口组患者生理功能、社会功能、生理职能、精神健康、情感职能和总体健康评分均高于对照组患者,差异均有统计学意义(P﹤0.05)。术后随访36个月,环切口组失访2例,对照组失访4例,两组患者局部复发率、腋窝淋巴结复发率、远处转移率比较,差异均无统计学意义(P﹥0.05)。环切口组患者的并发症总发生率为17.14%,低于对照组患者的31.43%,差异有统计学意义(P﹤0.05)。结论环乳晕切口手术治疗乳腺癌效果较好,且手术创伤较小、术后患者生存质量更好。

Objective To explore the effect of circum-areola incision in breast cancer patients.Method 140 breast cancer patients were randomly divided into the circum-areola incision group(n=70,treated with circum-areola incision)and the control group(n=70,treated with tumor surface incision).The operation-related indicators,including operation time,axillary extubation time and axillary drainage time of the patients were compared;the quality of life by using the MOS 36-item short form health survey(SF-36),recurrence and complications of the two groups were compared.Result The axillary extubation time and axillary drainage time of the circum-areola incision group were significantly shorter,the operation time longer than those of the control group(P<0.05).At 6 months after surgery,the scores of physiological function,social function,physiological function,mental health,and emotional function of the two groups were higher than those of before operation in this group,and the overall health scores of physiological function,social function,physiological function,vitality,mental health,and emotional function of the circum-areola incision group were significantly higher than those of the control group(P<0.05).After 36 months of follow-up,2 cases were lost to follow-up in the circum-areola incision group and 4 cases in the control group.There was no significant difference in the local recurrence rate,axillary lymph node recurrence rate,and distant metastasis rate between the two groups(P>0.05).The overall incidence of complications in the circum-areola incision group(17.14%)was significantly lower than that in the control group(31.43%)(P<0.05).Conclusion Circum-areola incision has a better effect on breast cancer,with less surgical trauma and better quality of life for patients after surgery.