不同时机口服西甲硅油对肠镜检查效果的影响

The effect of oral simethicone at different times on colonoscopy

目的研究肠镜检查中不同时机口服西甲硅油对肠镜检查效果的影响。方法采用回顾性分析方法,研究对象为2019年1月至12月南京中医药大学附属医院收治入院的72例肠镜检查患者,根据不同用药方式分为2组,各36例。对照组口服3包复方聚乙二醇电解质散,肠镜检查前一晚20:00口服1包复方聚乙二醇电解质散,肠镜检查当日检查前4~6 h口服2包复方聚乙二醇电解质散。观察组分别在3个不同时机加服1支西甲硅油,分别设定为观察A组(开始喝第一包复方聚乙二醇电解质散)、观察B组(喝最后一包复方聚乙二醇电解质散)及观察C组(肠镜检查前2 h),3组各12例。比较对照组与观察组中A组、B组及C组患者的肠道内气泡含量、肠道清洁度及肠镜检查耐受度。结果对照组肠道内气泡含量分级中0级比率、肠道清洁度、无不适率依次为22.22%、(7.49±1.25)分、30.56%;观察A组依次为8.33%、(7.57±1.27)分、33.33%;观察B组依次为41.67%、(7.53±1.30)分、50.00%;观察C组依次为91.67%、(7.62±1.28)分、91.67%。与对照组、观察A组及观察B组相比,观察C组肠道内气泡含量明显更低,肠镜检查耐受度更高,差异有统计学意义(P<0.05);4组患者的肠道清洁度比较,差异无统计学意义(P>0.05)。结论结肠镜检查前2 h服用西甲硅油的效果显著,可进一步降低患者肠道内气泡含量,提升其肠镜检查耐受度。

Objective To study the effect of oral simethicone at different times on colonoscopy.Methods Using a retrospective analysis method,the subjects of the study were 72 colonoscopy patients admitted to Affiliated Hospital of Nanjing University of Chinese Medicine from January to December 2019.They were divided into two groups according to different medication methods,with 36 cases in each group.The control group took 3 packets of compound polyethylene glycol electrolyte powder,1 packet of compound polyethylene glycol electrolyte powder at 20:00 the night before colonoscopy,and 2 packets of compound polyethylene glycol 4-6 h before the day of colonoscopy.Electrolyte powder;the observation group was given a piece of simethicone at three different times,respectively,set to observation group A(start to drink the first packet of compound polyethylene glycol electrolyte powder),observation group B(drink the last packet of compound poly Glycol Electrolyte Powder)and observation group C(2 h before colonoscopy),12 cases in each of the three groups.Compare the intestinal air bubble content,intestinal cleanliness and colonoscopy tolerance between the control group and the observation group in groups A,B and C.Results The 0 grade rate,intestinal cleanliness,and non-discomfort rate in the control group's intestinal air bubble content classification were 22.22%,(7.49±1.25)points,and 30.56%.The group A were 8.33%,(7.57±1.27)points,and 33.33%;the group B were 41.67%,(7.53±1.30)points,50.00%;the group C were 91.67%,(7.62±1.28)points,91.67%in sequence.The content of air bubbles in the intestinal tract of observation group C was significantly lower than that of control group,observation group A and observation group B,and colonoscopy tolerance was higher than that of control group,observation group A and observation group B.The difference was statistically significant(P<0.05).There was no statistically significant difference in intestinal cleanliness between the 4 groups(P>0.05).Conclusion The effect of taking simethicone 2 hours before colonoscopy is significant,which can further reduce the content of air bubbles in the patient's intestinal tract and improve the tolerance of colonoscopy.